Results 51 to 60 of about 2,509,978 (172)

Therapeutic potential of thioctic (alpha-lipoic) acid in patients with diabetes mellitus type 2 and metabolic associated fatty liver disease

Mìžnarodnij Endokrinologìčnij Žurnal
Background. Diabetes mellitus type 2 (T2DM) and metabolic associated fatty liver disease (MAFLD) are common metabolic diseases that are often accompanied by obesity, dyslipidemia and hypertension.
Yu.F. Marchuk, V.V. Vivsiannyk, I.I. Alieksieieva, D.R. Andriychuk   +3 more
doaj   +1 more source

Clinical efficacy of alprostadil combined with α-lipoic acid in the treatment of elderly patients with diabetic nephropathy

Open Medicine, 2017
To evaluate the effect and toxicity of alprostadil combined with thioctic acid injection in the treatment of patients with diabetic nephropathy (DN).
Hong Yan, Peng Jianyun, Cai Xiaoping, Zhang Xiaoru, Liao Yifei, Lan Lejian   +5 more
doaj   +1 more source

Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics

Advanced Science, Volume 13, Issue 49, 3 September 2026.
This Review highlights how surface and interfacial engineering governs the reliability, durability, and functional stability of mechanically coupled flexible electronics. By integrating fundamental interfacial theory, failure mechanisms, multiscale engineering strategies, and representative applications, it provides a design‐oriented framework for ...
Qian Wang, Fangfang Dai, Wei Wu
wiley   +1 more source

Metabolism of Thioctic Acid in Algae [PDF]

, 1956
Thioctic acid labeled with sulfur-35 has been prepared and i t s metabolism b y algae has been studied. It i s converted by the algae into a number of forms, all of which upon hydrolysis yield either the disulfide o r i t s sulfoxide.
Grisebach, Hans, Fuller, R C, Calvin, M., Fuller, R.C., Calvin, M   +4 more
core   +1 more source

Aquifer Microbial Communities Differentially Display Metabolisms Capable of Secondary Effects on Uranium Speciation Across a Former Metal Processing Site

Environmental Microbiology, Volume 28, Issue 9, September 2026.
We performed microbial membership and metabolism measurements across a uranium‐contaminated site's surface and ground waters, then performed analyses relating these metrics to geochemistry at the site. Findings showed variations in the membership, yet mainly similar functional capabilities.
Catherine J. Pettinger, Allondra M. Woods, Raymond H. Johnson, Charles J. Paradis, Erica L.‐W. Majumder   +4 more
wiley   +1 more source

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

BioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen, Thomas Roeder, Gerald Rimbach   +2 more
wiley   +1 more source

Do choline alphoscerate and thioctic acid prevent the cerebrovascular alterations in spontaneously hypertensive rats?

, 2021
Do choline alphoscerate and thioctic acid prevent the cerebrovascular alterations in spontaneously hypertensive ...
Roy P., Tayebati S. K., Traini E., Martinelli I., Tomassoni D., Amenta F.   +5 more
core   +1 more source

Efficacy and Safety of Pregabalin and Alpha‐Lipoic Acid Combination in Patients With Painful Diabetic Peripheral Neuropathy: A Randomized, Open‐Label, Non‐Inferiority, Phase IV Clinical Trial and Subgroup Analysis (OPTIMUM Study)

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 6172-6183, July 2026.
ABSTRACT Aims To assess the efficacy and safety of alpha‐lipoic acid (ALA) and pregabalin, both as mono and combination therapy, for treating painful diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus, with the hypothesis that pregabalin monotherapy is non‐inferior to combination therapy.
Tae Jung Oh, Sang Soo Kim, Seung‐Hwan Lee, Hyuk‐Sang Kwon, Eun Sook Kim, Eun‐Jung Rhee, Hye Jin Yoo, Han Na Jang, Woo Je Lee, Eun Sook Kim, Sang Yong Kim, Gwanpyo Koh, Eun‐Gyoung Hong, Tae Sun Park, Jong Chul Won   +14 more
wiley   +1 more source

Morphology of cardiac and renal microvasculature in spontaneously hypertensive rat. Activity of thioctic acid [PDF]

, 2014
Accumulation of intimal vascular smooth muscle cells is a trait of atherosclerosis. Endothelial cells lining vascular luminal surface represent an important site of signalling and development of damage induced by reactive oxygen species (ROS) during ...
Innocent, Nwankwo E., Khosrow Tayebati, Seyed, Tomassoni, Daniele, Amenta, Francesco   +3 more
core   +3 more sources

Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He, Qiuhong Ouyang, Xinglv Chen, Qian Zhong, Xunhuan Song, Yujie Sun, Bingran Yu, Meng Qin   +7 more
wiley   +1 more source