Results 61 to 70 of about 2,509,978 (172)
Objective. We performed a systematic review of the literature to evaluate the effects of alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes mellitus. Research design and methods.
Gerritje S. Mijnhout +4 more
doaj +1 more source
Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley +1 more source
Thioctic acid modification of oligonucleotides using an H-phosphonate
The H-phosphonate of a derivative of thioctic acid (TA) was synthesized and used to introduce a disulfide moiety at the 5'-end of oligonucleotides. This method overcomes the difficulties experienced with the phosphoramidite approach when employing a ...
Graham, Duncan +2 more
core +4 more sources
Alcoholic polyneuropathy: ways of diagnostics and therapy
The article is devoted to the analysis of the pathogenetic mechanisms of the formation of alcoholic lesions of the peripheral nervous system. Various clinical forms of alcoholic polyneuropathy are considered, ways to diagnose using modern instrumental ...
O. V. Kurushina +2 more
doaj +1 more source
A randomized double-blind placebo-controlled trial of thioctic acid in migraine prophylaxis
peer reviewedBACKGROUND: Impaired mitochondrial phosphorylation potential may play a role in migraine pathogenesis. Metabolic enhancers, such as riboflavin or coenzyme Q, are effective in migraine prophylaxis and quasi-devoid of adverse effects. Thioctic
Ambrosini, Anna +6 more
core +1 more source
Introduction. Thioctic acid is used in the treatment of diseases that are characterized by lack of mitochondrial activity, which is responsible for the formation of free radicals. Widespread use of thioctic acid is due to the chemical structure.
I Kovalevska, O Ruban
doaj
Clinical Approaches to the Treatment of Diabetic Neuropathy
The article is devoted to the treatment of diabetic neuropathy. The described scheme of application of preparations of alpha-lipoic (thioctic) acid. Recently in Europe and the United States conducted a series of clinical studies that have shown that the ...
A.V. Kaminsky
doaj +1 more source
Drug utilisation trends in a physical rehabilitation hospital [PDF]
Background/Aim. Drug utilisation monitoring could identify drug-related problems and hence improve the awareness of irrational drug use. The objective of this study was to analyse the drug utilisation patterns in a rehabilitation hospital over the period
Ljubojević Gordana +7 more
doaj +1 more source
A nanobiosensor for fast and simultaneous determination of sweat glucose and ethanol is presented. Deposited oxidase enzymes consume oxygen in the presence of the substrates, and co‐deposited palladium nanoclusters catalyze the electrochemical oxygen reduction, basis of the detection.
Alejandro Rodríguez‐Penedo +3 more
wiley +1 more source
ACTIVITY OF THIOCTIC ACID ENANTIOMERS ON SPINAL CORD CHANGES CONSEQUENT TO PERIPHERAL NERVE INJURY
Peripheral neuropathies are disorders characterized by hyperalgesia and allodynia with impaired muscular sensitivity and functions. Oxidative stress, which is an imbalance between the production of free radicals and the antioxidant defence mechanisms
AMENTA, Francesco +5 more
core +1 more source

