Results 61 to 70 of about 2,509,978 (172)

Alpha Lipoic Acid for Symptomatic Peripheral Neuropathy in Patients with Diabetes: A Meta-Analysis of Randomized Controlled Trials

open access: yesInternational Journal of Endocrinology, 2012
Objective. We performed a systematic review of the literature to evaluate the effects of alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes mellitus. Research design and methods.
Gerritje S. Mijnhout   +4 more
doaj   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

open access: yesChemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Thioctic acid modification of oligonucleotides using an H-phosphonate

open access: yes, 2010
The H-phosphonate of a derivative of thioctic acid (TA) was synthesized and used to introduce a disulfide moiety at the 5'-end of oligonucleotides. This method overcomes the difficulties experienced with the phosphoramidite approach when employing a ...
Graham, Duncan   +2 more
core   +4 more sources

Alcoholic polyneuropathy: ways of diagnostics and therapy

open access: yesМедицинский совет, 2019
The article is devoted to the analysis of the pathogenetic mechanisms of the formation of alcoholic lesions of the peripheral nervous system. Various clinical forms of alcoholic polyneuropathy are considered, ways to diagnose using modern instrumental ...
O. V. Kurushina   +2 more
doaj   +1 more source

A randomized double-blind placebo-controlled trial of thioctic acid in migraine prophylaxis

open access: yes, 2007
peer reviewedBACKGROUND: Impaired mitochondrial phosphorylation potential may play a role in migraine pathogenesis. Metabolic enhancers, such as riboflavin or coenzyme Q, are effective in migraine prophylaxis and quasi-devoid of adverse effects. Thioctic
Ambrosini, Anna   +6 more
core   +1 more source

Study of pharmaco-technological properties of solid dispersions of thioctic acid obtained by micronization method

open access: yesAnnals of Mechnikov's Institute, 2018
Introduction. Thioctic acid is used in the treatment of diseases that are characterized by lack of mitochondrial activity, which is responsible for the formation of free radicals. Widespread use of thioctic acid is due to the chemical structure.
I Kovalevska, O Ruban
doaj  

Clinical Approaches to the Treatment of Diabetic Neuropathy

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2014
The article is devoted to the treatment of diabetic neuropathy. The described scheme of application of preparations of alpha-lipoic (thioctic) acid. Recently in Europe and the United States conducted a series of clinical studies that have shown that the ...
A.V. Kaminsky
doaj   +1 more source

Drug utilisation trends in a physical rehabilitation hospital [PDF]

open access: yesVojnosanitetski Pregled, 2019
Background/Aim. Drug utilisation monitoring could identify drug-related problems and hence improve the awareness of irrational drug use. The objective of this study was to analyse the drug utilisation patterns in a rehabilitation hospital over the period
Ljubojević Gordana   +7 more
doaj   +1 more source

Nanobiosensor Based on Catalytic Palladium Nanoclusters and Oxidases for Bianalyte Electrochemical Determination: Glucose and Ethanol in Sweat

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 16, 24 April 2026.
A nanobiosensor for fast and simultaneous determination of sweat glucose and ethanol is presented. Deposited oxidase enzymes consume oxygen in the presence of the substrates, and co‐deposited palladium nanoclusters catalyze the electrochemical oxygen reduction, basis of the detection.
Alejandro Rodríguez‐Penedo   +3 more
wiley   +1 more source

ACTIVITY OF THIOCTIC ACID ENANTIOMERS ON SPINAL CORD CHANGES CONSEQUENT TO PERIPHERAL NERVE INJURY

open access: yes, 2013
Peripheral neuropathies are disorders characterized by hyperalgesia and allodynia with impaired muscular sensitivity and functions. Oxidative stress, which is an imbalance between the production of free radicals and the antioxidant defence mechanisms
AMENTA, Francesco   +5 more
core   +1 more source

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