Diabetes and alpha lipoic acid [PDF]
Frontiers in Pharmacology, 2011 Diabetes mellitus is a multi-faceted metabolic disorder where there is increased oxidative stress that contributes to the pathogenesis of this debilitating disease.
Issy eLaher
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Electrochemical Behavior of the Super Antioxidant, α-Lipoic Acid
International Journal of Electrochemical Science, 2011 We have investigated the complex cyclic voltammetric behaviour of the sodium salt of α-lipoic acid in the absence and presence of the background electrolytes, sodium chloride and phosphate buffer.
C.V. Krishnan, M. Garnett
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Nanotechnological Approaches to Enhance the Potential of α-Lipoic Acid for Application in the Clinic
Antioxidantsα-lipoic acid is a naturally occurring compound with potent antioxidant properties that helps protect cells and tissues from oxidative stress. Its incorporation into nanoplatforms can affect factors like bioavailability, stability, reactivity, and ...
Chiara Bellini +3 more
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Spectroscopic Studies of 6-Membered Lipoic Acid Derivative, 1,2,3-Trithiane-4-pentanoic Acid, and Its Characteristic Stereochemical Profiles [PDF]
MoleculesInserting a sulfur atom into the 1,2-dithiolane ring of lipoic acid (LA racemate) is a promising approach for improving the diversity of lipoic acid (LA racemate).
Seiichi Matsugo +3 more
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In Silico and In Vitro Investigation of Apoptosis-Mediated Antiproliferative Activity of Capsaicin and Alpha-Lipoic Acid Against Prostate Cancer Cells [PDF]
Current Issues in Molecular BiologyNatural products are widely used in the treatment of cancer due to the side effects of chemotherapeutics, and a large number of natural compounds have been reported to have anticancer activities in different types of cancer.
Ogunc Meral +9 more
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Comparative Characteristics of Dosage Forms of α-Lipoic Acid [PDF]
E3S Web of Conferences, 2020 α-Lipoic acid is a fatty acid, which in its physiological effect is on a par with vitamins and minerals, is a vitamin-like substance (vitamin N). A review of clinical trials of the effectiveness of α-lipoic acid in evidence-based diseases is presented ...
Shkolnikova Marina +2 more
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Synergistic antihyperglycemic effect of alpha lipoic acid with antidiabetic agents in the normoglycemic and streptozotocin-induced type 2 diabetic rats [PDF]
Acta Poloniae Pharmaceutica, 2023 The current study's main goal was to assess the supplementation effect of alpha lipoic acid with antidiabetic medications (metformin and sitagliptin) on normal and streptozotocin-induced blood glucose levels in normal and streptozotocin-induced diabetic ...
Rawsan Ali Sabri +2 more
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R-enantiomer of α-lipoic acid. Opportunities and prospects for clinical use
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 The paper presents an analysis of current literature data on the use of the R-enantiomer of α-lipoic acid as an antihypertensive treatment in patients with hypertension and metabolic syndrome.
N.A. Kravchun +2 more
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Frontiers in Bioengineering and Biotechnology, 2020 Lipoic acid is a valuable organosulfur compound used as an antioxidant for dietary supplementation, and potentially anti-diabetic and anti-cancer. Currently, lipoic acid is obtained mainly through chemical synthesis, which requires toxic reagents and ...
Binbin Chen +7 more
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Encapsulation of α-Lipoic Acid in Halloysite Nanotubes
Applied Sciences, 2023 A nanocomposite material based on halloysite and α-lipoic acid was studied. The kinetics of the degradation process of α-lipoic acid under the influence of ultraviolet radiation and thermal stress in its native state and in the composition of a ...
Andrii Melnyk +2 more
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