Results 1 to 10 of about 40,711 (162)

Electrochemical Behavior of the Super Antioxidant, α-Lipoic Acid

open access: yesInternational Journal of Electrochemical Science, 2011
We have investigated the complex cyclic voltammetric behaviour of the sodium salt of α-lipoic acid in the absence and presence of the background electrolytes, sodium chloride and phosphate buffer.
C.V. Krishnan, M. Garnett
doaj   +3 more sources

Spectroscopic Studies of 6-Membered Lipoic Acid Derivative, 1,2,3-Trithiane-4-pentanoic Acid, and Its Characteristic Stereochemical Profiles [PDF]

open access: yesMolecules
Inserting a sulfur atom into the 1,2-dithiolane ring of lipoic acid (LA racemate) is a promising approach for improving the diversity of lipoic acid (LA racemate).
Seiichi Matsugo   +3 more
doaj   +2 more sources

In Silico and In Vitro Investigation of Apoptosis-Mediated Antiproliferative Activity of Capsaicin and Alpha-Lipoic Acid Against Prostate Cancer Cells [PDF]

open access: yesCurrent Issues in Molecular Biology
Natural products are widely used in the treatment of cancer due to the side effects of chemotherapeutics, and a large number of natural compounds have been reported to have anticancer activities in different types of cancer.
Ogunc Meral   +9 more
doaj   +2 more sources

Synergistic antihyperglycemic effect of alpha lipoic acid with antidiabetic agents in the normoglycemic and streptozotocin-induced type 2 diabetic rats [PDF]

open access: yesActa Poloniae Pharmaceutica, 2023
The current study's main goal was to assess the supplementation effect of alpha lipoic acid with antidiabetic medications (metformin and sitagliptin) on normal and streptozotocin-induced blood glucose levels in normal and streptozotocin-induced diabetic ...
Rawsan Ali Sabri   +2 more
doaj   +1 more source

Comparative Characteristics of Dosage Forms of α-Lipoic Acid [PDF]

open access: yesE3S Web of Conferences, 2020
α-Lipoic acid is a fatty acid, which in its physiological effect is on a par with vitamins and minerals, is a vitamin-like substance (vitamin N). A review of clinical trials of the effectiveness of α-lipoic acid in evidence-based diseases is presented ...
Shkolnikova Marina   +2 more
doaj   +1 more source

R-enantiomer of α-lipoic acid. Opportunities and prospects for clinical use

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2021
The paper presents an analysis of current literature data on the use of the R-enantiomer of α-lipoic acid as an antihypertensive treatment in patients with hypertension and metabolic syndrome.
N.A. Kravchun   +2 more
doaj   +1 more source

Mechanism-Driven Metabolic Engineering for Bio-Based Production of Free R-Lipoic Acid in Saccharomyces cerevisiae Mitochondria

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Lipoic acid is a valuable organosulfur compound used as an antioxidant for dietary supplementation, and potentially anti-diabetic and anti-cancer. Currently, lipoic acid is obtained mainly through chemical synthesis, which requires toxic reagents and ...
Binbin Chen   +7 more
doaj   +1 more source

Encapsulation of α-Lipoic Acid in Halloysite Nanotubes

open access: yesApplied Sciences, 2023
A nanocomposite material based on halloysite and α-lipoic acid was studied. The kinetics of the degradation process of α-lipoic acid under the influence of ultraviolet radiation and thermal stress in its native state and in the composition of a ...
Andrii Melnyk   +2 more
doaj   +1 more source

Alpha-Lipoic Acid Protects Co-Exposure to Lead and Zinc Oxide Nanoparticles Induced Neuro, Immuno and Male Reproductive Toxicity in Rats

open access: yesFrontiers in Pharmacology, 2021
We evaluated the neuro-, immuno-, and male reproductive toxicity of zinc oxide nanoparticles (ZnO NPs) alone and in combination with lead acetate. We also studied the therapeutic role of α-lipoic acid postexposure.
Monika S. Deore   +4 more
doaj   +1 more source

Encapsulation of α-lipoic acid intochitosan and alginate/gelatin hydrogel microparticles and its in vitro antioxidant activity [PDF]

open access: yesHemijska Industrija, 2016
Alpha-lipoic acidis an organosulphur compound well-known for its therapeutic potential and antioxidant properties. However, the effective use of α-lipoic acid depends on biological plasma half-life and its preserving stability, which could be ...
Vidović Bojana B.   +6 more
doaj   +1 more source

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