Results 41 to 50 of about 40,812 (258)

Dual-modal SERS/fluorescence AuNP probe for mitochondrial imaging [PDF]

, 2017
A novel SERS/fluorescent multimodal imaging probe for mitochondria has been synthesised using 12 nm diameter gold nanoparticles (AuNP) surface functionalised with a rhodamine thiol derivative ligand.
Beija, Best, Brindle, Chen, Doubrovin, Duchen, Enüstün, Frens, Ghosh, Gonçalves, Hockings, Huang, Jaworska, Jennings, Kimling, Lavis, Lee, Lee, Lefevre, Lin, Longmire, Mayer, Pan, Rivas, Rivas, Saha, Scaduto, Stasiuk, Stasiuk, Stuchinskaya, Suksai, Sun, Sung, Wang, You, Yuan, Zhou   +36 more
core   +1 more source

Biosynthesis of Lipoic Acid in Arabidopsis: Cloning and Characterization of the cDNA for Lipoic Acid Synthase [PDF]

Plant Physiology, 1998
Abstract Lipoic acid is a coenzyme that is essential for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. We report here the isolation and characterization of LIP1 cDNA for lipoic acid synthase of Arabidopsis.
R, Yasuno, H, Wada
openaire   +2 more sources

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Safety and Efficacy of Alpha Lipoic Acid During 4 Years of Observation: A Retrospective, Clinical Trial in Healthy Subjects in Primary Prevention

Drug Design, Development and Therapy, 2020
Giuseppe Derosa,1,2 Angela D’Angelo,2 Paola Preti,1 Pamela Maffioli1 1Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; 2Laboratory of Molecular Medicine, University of Pavia, Pavia, ItalyCorrespondence: Giuseppe ...
Derosa G, D'Angelo A, Preti P, Maffioli P   +3 more
doaj  

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Impact of Dietary α-Lipoic Acid on Antioxidant Potential of Broiler Thigh Meat

Journal of Chemistry, 2015
The lipid oxidation depressed the meat quality and can be triggered during industrial processing. The current study was designed to assess the antioxidant activity of thigh meat and meat products enriched with natural antioxidants (α-lipoic acid and α ...
Muhammad Issa Khan, Komal Shehzad, Muhammad Sajid Arshad, Amna Sahar, Muhammad Asim Shabbir, Muhammad Saeed   +5 more
doaj   +1 more source

Estabilização do ácido lipoico via encapsulação em nanocápsulas poliméricas planejadas para aplicação cutânea Stabilization of lipoic acid by encapsulation in polymeric nanocapsules designed for cutaneous administration

Química Nova, 2009
This work reports the development of polymeric nanocapsules containing lipoic acid prepared by interfacial deposition of poli(ε-caprolactona). The suspensions showed acid pH and encapsulation efficiencies from 77 to 90%.
Irene Clemes Külkamp, Karina Paese, Sílvia Stanisçuaski Guterres, Adriana Raffin Pohlmann   +3 more
doaj   +1 more source

Oral plus vaginal alpha-lipoic acid in women at risk for preterm delivery [PDF]

, 2018
Objective: The etiology of preterm labor is multifactorial. An inflammatory response is always involved with the activation of NF-kB that determines synthesis and release of inflammatory molecules, implicated in fetal membrane activation, cervical ...
Giallombardo V., Guardino M., Mocera G., Venezia R, Vitrano G.   +4 more
core  

Lipoic acid and diabetes II: Mode of action of lipoic acid

Journal of Biosciences, 1985
Intraperitoneal administration of lipoic acid (10 mg/100 g) does not effect changes in serum insulin levels in normal and alloxan diabetic rats, while normalising increased serum pyruvate, and impaired liver pyruvic dehydrogenase characteristic of the diabetic state.
V. M. Gandhi, S. S. Wagh, C. V. Natraj, K. K. G. Menon   +3 more
openaire   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source