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Nanotechnological Approaches to Enhance the Potential of α-Lipoic Acid for Application in the Clinic [PDF]

open access: yesAntioxidants
α-lipoic acid is a naturally occurring compound with potent antioxidant properties that helps protect cells and tissues from oxidative stress. Its incorporation into nanoplatforms can affect factors like bioavailability, stability, reactivity, and ...
Chiara Bellini   +3 more
doaj   +4 more sources

Electrochemical Behavior of the Super Antioxidant, α-Lipoic Acid

open access: yesInternational Journal of Electrochemical Science, 2011
We have investigated the complex cyclic voltammetric behaviour of the sodium salt of α-lipoic acid in the absence and presence of the background electrolytes, sodium chloride and phosphate buffer.
C.V. Krishnan, M. Garnett
doaj   +3 more sources

Comparative Characteristics of Dosage Forms of α-Lipoic Acid [PDF]

open access: yesE3S Web of Conferences, 2020
α-Lipoic acid is a fatty acid, which in its physiological effect is on a par with vitamins and minerals, is a vitamin-like substance (vitamin N). A review of clinical trials of the effectiveness of α-lipoic acid in evidence-based diseases is presented ...
Shkolnikova Marina   +2 more
doaj   +1 more source

Encapsulation of α-Lipoic Acid in Halloysite Nanotubes

open access: yesApplied Sciences, 2023
A nanocomposite material based on halloysite and α-lipoic acid was studied. The kinetics of the degradation process of α-lipoic acid under the influence of ultraviolet radiation and thermal stress in its native state and in the composition of a ...
Andrii Melnyk   +2 more
doaj   +1 more source

R-enantiomer of α-lipoic acid. Opportunities and prospects for clinical use

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2021
The paper presents an analysis of current literature data on the use of the R-enantiomer of α-lipoic acid as an antihypertensive treatment in patients with hypertension and metabolic syndrome.
N.A. Kravchun   +2 more
doaj   +1 more source

Encapsulation of α-lipoic acid intochitosan and alginate/gelatin hydrogel microparticles and its in vitro antioxidant activity [PDF]

open access: yesHemijska Industrija, 2016
Alpha-lipoic acidis an organosulphur compound well-known for its therapeutic potential and antioxidant properties. However, the effective use of α-lipoic acid depends on biological plasma half-life and its preserving stability, which could be ...
Vidović Bojana B.   +6 more
doaj   +1 more source

The Effect of Alpha-Lipoic Acid against Methotrexate on Testicular Damage in Rats

open access: yesJournal of Contemporary Medicine, 2023
Aim: The toxic effects of methotrexate, a chemotherapeutic, on the testicles is an important side effect. Methotrexate impairs spermatogenesis and fertility and causes oligospermia. In this study, we aimed to minimize the testicular toxicity, those being
Ahmetcan Varel   +5 more
doaj   +1 more source

Efficacy of the R(+)-enantiomer of alpha-lipoic acid in clinical practice

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2021
The article presents current data from the scientific medical literature on the effective use of the R(+)-enantiomer of α-lipoic acid in various pathological conditions.
N.О. Kravchun, I.P. Dunaieva
doaj   +1 more source

Alpha-Lipoic Acid Protects Co-Exposure to Lead and Zinc Oxide Nanoparticles Induced Neuro, Immuno and Male Reproductive Toxicity in Rats

open access: yesFrontiers in Pharmacology, 2021
We evaluated the neuro-, immuno-, and male reproductive toxicity of zinc oxide nanoparticles (ZnO NPs) alone and in combination with lead acetate. We also studied the therapeutic role of α-lipoic acid postexposure.
Monika S. Deore   +4 more
doaj   +1 more source

Rational Design and Experimental Research on the Self-Assembled System of Thermosensitive Molecularly Imprinted Polymers Formed by α-Lipoic Acid and N-Vinyl Caprolactam

open access: yesInternational Journal of Polymer Science, 2021
In this paper, the main work was to study the theoretical self-assembly process of thermosensitive molecularly imprinted polymers (MIPs) for α-lipoic acid and to investigate thermosensitive functional monomers through density functional theory ...
Yu-Qin Chen   +4 more
doaj   +1 more source

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