Nanotechnological Approaches to Enhance the Potential of α-Lipoic Acid for Application in the Clinic [PDF]
Antioxidantsα-lipoic acid is a naturally occurring compound with potent antioxidant properties that helps protect cells and tissues from oxidative stress. Its incorporation into nanoplatforms can affect factors like bioavailability, stability, reactivity, and ...
Chiara Bellini +3 more
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Amelioration of autophagy and inflammatory signaling pathways via α-lipoic acid, burdock and bee pollen versus lipopolysaccharide-induced insulin resistance in murine model [PDF]
Heliyon, 2023 Lipopolysaccharide (LPS) has previously been implicated in insulin resistance by generating an innate immune response and activating inflammatory cascades.
Rehab M. Abdel-Megeed, Mai O. Kadry
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Effects of α-Lipoic Acid Supplementation on Growth Performance, Liver Histology, Antioxidant and Related Genes Expression of Hybrid Grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂) [PDF]
AntioxidantsThis study aimed to assess the impact of α-lipoic acid on the growth performance, antioxidant capacity and immunity in hybrid groupers (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus) fed with a high-lipid diet.
Weibin Huang +9 more
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Comparative Characteristics of Dosage Forms of α-Lipoic Acid [PDF]
E3S Web of Conferences, 2020 α-Lipoic acid is a fatty acid, which in its physiological effect is on a par with vitamins and minerals, is a vitamin-like substance (vitamin N). A review of clinical trials of the effectiveness of α-lipoic acid in evidence-based diseases is presented ...
Shkolnikova Marina +2 more
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Encapsulation of α-Lipoic Acid in Halloysite Nanotubes
Applied Sciences, 2023 A nanocomposite material based on halloysite and α-lipoic acid was studied. The kinetics of the degradation process of α-lipoic acid under the influence of ultraviolet radiation and thermal stress in its native state and in the composition of a ...
Andrii Melnyk +2 more
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R-enantiomer of α-lipoic acid. Opportunities and prospects for clinical use
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 The paper presents an analysis of current literature data on the use of the R-enantiomer of α-lipoic acid as an antihypertensive treatment in patients with hypertension and metabolic syndrome.
N.A. Kravchun +2 more
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Encapsulation of α-lipoic acid intochitosan and alginate/gelatin hydrogel microparticles and its in vitro antioxidant activity [PDF]
Hemijska Industrija, 2016 Alpha-lipoic acidis an organosulphur compound well-known for its therapeutic potential and antioxidant properties. However, the effective use of α-lipoic acid depends on biological plasma half-life and its preserving stability, which could be ...
Vidović Bojana B. +6 more
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The Effect of Alpha-Lipoic Acid against Methotrexate on Testicular Damage in Rats
Journal of Contemporary Medicine, 2023 Aim: The toxic effects of methotrexate, a chemotherapeutic, on the testicles is an important side effect. Methotrexate impairs spermatogenesis and fertility and causes oligospermia. In this study, we aimed to minimize the testicular toxicity, those being
Ahmetcan Varel +5 more
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Efficacy of the R(+)-enantiomer of alpha-lipoic acid in clinical practice
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 The article presents current data from the scientific medical literature on the effective use of the R(+)-enantiomer of α-lipoic acid in various pathological conditions.
N.О. Kravchun, I.P. Dunaieva
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Frontiers in Pharmacology, 2021 We evaluated the neuro-, immuno-, and male reproductive toxicity of zinc oxide nanoparticles (ZnO NPs) alone and in combination with lead acetate. We also studied the therapeutic role of α-lipoic acid postexposure.
Monika S. Deore +4 more
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