Results 41 to 50 of about 3,332,267 (201)
The protective effect of α-lipoic acid in doxorubicin induced cardiotoxicity in rats.
, 2008 This study examined the protective effects of α-lipoic acid in rats exposed to a cardiotoxic dose of the widely used chemotherapy agent doxorubicin. α-Lipoic acid significantly enhanced the survival of rats exposed to a lethal dose of doxorubicin (p& ...
Ramadan, Waile.
core +3 more sources
Bottlebrush Polyolefin Sulfones as Triggerable and Degradable Pressure‐Sensitive Adhesives
Angewandte Chemie, EarlyView.A grafting‐through alternating copolymerization strategy yields poly(norbornene sulfone) bottlebrush polymers with high molar mass. These materials function as additive‐free pressure‐sensitive adhesives. The incorporation of cleavable sulfone units enables rapid breakdown under mild alkaline conditions, providing a pathway toward sustainable, high ...
Clark Vu +5 more
wiley +2 more sources
Медицинский совет, 2016 α-Lipoic acid (thioctic) (ALA) is the most applicable pharmacological drug for treatment of diabetic polyneuropathy. The articles explores the results of experimental studies on α-Lipoic acid effect upon formation mechanisms of peripheral nerves ...
I. A. Strokov, A. S. Phokina
doaj +1 more source
Ecotoxicology and Environmental Safety, 2023 High environment ammonia (HEA) poses a deadly threat to aquatic animals and indirectly impacts human healthy life, while nutritional regulation can alleviate chronic ammonia toxicity. α-lipoic acid exhibits antioxidative effects in both aqueous and lipid
Zihao Yan +6 more
doaj +1 more source
Advanced Science, EarlyView.A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu +12 more
wiley +1 more source
AntioxidantsThis study aimed to assess the impact of α-lipoic acid on the growth performance, antioxidant capacity and immunity in hybrid groupers (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus) fed with a high-lipid diet.
Weibin Huang +9 more
doaj +1 more source
, 2014 Objective: α-Lipoic acid (α-LA) is a natural occurring antioxidant with beneficial effects on obesity. The aim of this study was to investigate the putative effects of α-LA on triglyceride accumulation and lipogenesis in subcutaneous adipocytes from ...
Patricia Pérez-Matute +17 more
core +1 more source
Advanced Science, EarlyView.PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang +5 more
wiley +1 more source
Lipoic acid assembly on 2-oxoacid dehydrogenases in E.coli [PDF]
, 2011 Lipoic acid is a covalently attached cofactor essential for the activity of 2-oxoacid dehydrogenases and the glycine cleavage system. In the absence of lipoic acid modification the dehydrogenases are inactive and aerobic metabolism is blocked.
El Haj Hassan, Bachar H.
core
Attenuating Effect of Spirulina Platensis and Alpha-lipoic acid against Aspartame induced Oxidative stress and Brain damage in Rabbits [PDF]
Benha Veterinary Medical Journal, 2019 Spirulina and lipoic acid has been considered as one of the most effective in anti- oxidative stress and anti-inflammatory activity.Aspartame (ASP) is one of the mostwidely used (artificial sweeteners)used in a variety of foods and feeds.This study was ...
Mahamoud Arafa +3 more
doaj +1 more source