Results 21 to 30 of about 3,332,267 (201)
Alpha-Lipoic Acid for the Prevention of Diabetic Macular Edema [PDF]
, 2011 Introduction: To evaluate the effect of alpha-lipoic acid (ALA) on the occurrence of diabetic macular edema. Methods: Randomized, double-blind, placebo-controlled, multicenter, multinational study. Patients were randomized to the treatment group with 600
Haritoglou, Christos +10 more
core +1 more source
Redox Biology, 2018 Alzheimer's disease (AD) is the most common neurodegenerative disease and is characterized by neurofibrillary tangles (NFTs) composed of Tau protein. α-Lipoic acid (LA) has been found to stabilize the cognitive function of AD patients, and animal study findings have confirmed its anti-amyloidogenic properties.
Yan-Hui Zhang +10 more
openaire +3 more sources
Toxicology Reports, 2017 The aim of this study was to evaluate the probable protective effect of α-lipoic acid against testicular toxicity in rats exposed to carbimazole during the embryonic period. Time-mated pregnant rats were exposed to carbimazole from the embryonic days 9-21.
P. Prathima +7 more
openaire +3 more sources
Knockout studies reveal an important role of plasmodium lipoic acid protein ligase a1 for asexual blood stage parasite survival [PDF]
, 2009 Lipoic acid (LA) is a dithiol-containing cofactor that is essential for the function of a-keto acid dehydrogenase complexes. LA acts as a reversible acyl group acceptor and 'swinging arm' during acyl-coenzyme A formation.
Sylke Müller +12 more
core +2 more sources
Medicine, 2022 . Background:. Diabetic nephropathy (DN) is a common microvascular complication of diabetes, which poses a serious threat to the health and life of patients.
Shengfu Jiao, MB +4 more
doaj +1 more source
Heliyon, 2023 Lipopolysaccharide (LPS) has previously been implicated in insulin resistance by generating an innate immune response and activating inflammatory cascades.
Rehab M. Abdel-Megeed, Mai O. Kadry
doaj +1 more source
Synthesis of R(+)-α-lipoic acid [PDF]
, 1987 An efficient enantiospecific synthesis of R(+)-α-lipoic acid (1) a prosthetic group and a vital cofactor in -α-keto acids decarboxylation is ...
Purandare, Ashok V. +3 more
core +1 more source
BMC Endocrine Disorders, 2021 Background Diabetic nephropathy (DN) is one of the most serious microvascular complications of diabetes, valsartan and α-lipoic acid alone or in combination has been used for the treatment of patients with DN.
Fangfang Sun, Deqi Jiang, Juanjuan Cai
doaj +1 more source
Protective Effects of Alpha Lipoic Acid Against Ionizing Radiation- Induced Hepatotoxicity in Rats
, 2023 Objective: Radiation is used to treat cancer but causes serious complications, such as liver toxicity. In this study, the protective effects of alpha lipoic acid against the unwanted effects of radiation used in many cancer treatments which can cause ...
Laloğlu, Abubekir +5 more
core +1 more source
α‑Lipoic Acid Alleviated Fluoride-Induced Hepatocyte Injury via Inhibiting Ferroptosis
, 2022 Fluoride is widely used in agricultural production and food packaging. Excessive fluoride in water and food is a serious threat to liver health. α-Lipoic acid, a natural free radical scavenger, has hepatoprotective properties.
Yangfei Zhao (11942800) +6 more
core +1 more source