Results 31 to 40 of about 3,332,267 (201)
Lipids in Health and Disease, 2011 Obese subjects with impaired glucose tolerance (IGT) are more susceptible than healthy individuals to oxidative stress and cardiovascular disease.
McNeilly Andrea M +7 more
doaj +1 more source
Protective Effects of α-lipoic acid on Biological changes Induced by α- cypermethrin in Testis Rats [PDF]
Journal of Bioscience and Applied Research, 2018 a-cypermethrin is one of the most potent insecticides used worldwide. This study was planned to evaluate the possible role of a-lipoic acid in a-cypermethrin induced toxicity in rats.
A. Sedky, A. Ali
doaj +1 more source
α-Lipoic Acid Alleviates Hepatic Lipid Deposition by Inhibiting FASN Expression via miR-3548 in Rats
, 2021 Excessive liver lipid deposition is a vital risk factor for the development of many diseases. Here, we fed Sprague-Dawley rats with a control or α-lipoic acid-supplemented diet (0.2%) for 5 weeks to elucidate the effects of α-lipoic acid on preventive ...
Wenqiang Ma +5 more
core +1 more source
Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids
Angewandte Chemie, EarlyView.Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar +2 more
wiley +2 more sources
Novel lipid derivatives for health benefits [PDF]
, 2013 Obesity is a public health concern and requires effective management with multiple approaches. Dietary supplements of bioactive compounds that can improve fatty acid oxidation and thermogenesis are currently in focus to develop anti-obese food ...
Madawala, Samanthi R. P.
core +1 more source
Closed‐Loop Recyclable Solid Polymer Electrolytes via Dynamic Lipoate Cross‐Linking
Angewandte Chemie, EarlyView.A visible‐light‐driven, closed‐loop recyclable solid polymer electrolyte is built from a bio‐derived lipoate cross‐linker, poly(ethylene glycol) bis(lipoate) (PEG‐LP2), synthesized from α‐lipoic acid. Dynamic disulfide exchange enables efficient DBU‐catalyzed depolymerization and photo‐repolymerization, regenerating membranes that retain high ionic ...
Qian Huang +6 more
wiley +2 more sources
Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine
Advanced Healthcare Materials, EarlyView.Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi +2 more
wiley +1 more source
Angewandte Chemie, EarlyView.A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy +7 more
wiley +2 more sources
Heliyon, 2019 Aim: α-Lipoic acid exerts a powerful antioxidant effect by acting as a free radical scavenger and inducing endogenous antioxidants such as vitamin E and glutathione. In the present study, we examined the effects of α-lipoic acid on cardiac dysfunction in
Daisuke Kurumazuka +6 more
doaj +1 more source
Advanced Science, EarlyView.To effectively reverse TMZ resistance, this work proposes a cuproptosis‐mediated positive feedback loop that integrates mitochondrial dysfunction, ATP depletion, AMPK‐p53 signaling, and glycolytic inhibition, ultimately amplifying cell death. This cuproptosis‐mediated feedback loop simultaneously disrupts multiple resistance pathways in GBM, including ...
Wenjie Feng +9 more
wiley +1 more source