Results 61 to 70 of about 3,332,267 (201)

Role of Alpha-lipoic acid and Naringin in Modulating Bisphenol-A Induced Perturbations of Prostate in Adult Rats (Histological and Immunohistochemical Study) [PDF]

The Egyptian Journal of Histology
Introduction: Bisphenol-A is categorized as an endocrine disruptor. A biological thiol antioxidant that lowers oxidative damage is alpha-lipoic acid. Flavone naringin has antioxidant properties.Aim of the Work: To evaluate the ability of α-Lipoic Acid ...
Nancy Awad, Mona Mohammed, Omayma Mahmoud, Amani Almallah   +3 more
doaj   +1 more source

Benfotiamine and Alpha-Lipoic Acid in the Treatment of Diabetic Cardiovascular Autonomic Neuropathy (Review of Literature and Own Researches)

Mìžnarodnij Endokrinologìčnij Žurnal, 2014
The analysis of current views on the mechanisms of fat-soluble form of vitamin B1 (benfotiamine) and α-lipoic acid action, in particular features of their impact on carbohydrate and lipid metabolism, endothelial function, hemodynamics, vessel stiffness ...
V.O. Sergiyenko
doaj   +1 more source

Delayed hypersensitivity to α-lipoic acid: look at dietary supplements.

, 2015
Delayed hypersensitivity to α-lipoic acid: look at dietary ...
Buonomo, Alessandro, Nucera, Eleonora, Rizzi, Angela, Schiavino, Domenico   +3 more
core   +1 more source

Assessment of the role of α-lipoic acid against the oxidative stress of induced iron overload

Journal of Radiation Research and Applied Sciences, 2015
This work was aimed to study the protective role of α-lipoic acid against the oxidative damage of induced iron overload. Iron (Fe) overload is a complication of the treatment, by chronic transfusion, of a number of genetic diseases associated with ...
Yasser F. Ali, Omar S. Desouky, Nabila S. Selim, Khairy. M. Ereiba   +3 more
doaj   +1 more source

Transformative Masked Ortho‐Quinone Chemistry: From Direct Guaiacol Activation to Lignin‐Based Adhesives

Angewandte Chemie International Edition, EarlyView.
Renewable guaiacols are rapidly oxidized by phenyliodine(III)diacetate to masked ortho‐quinones, giving a new class of monomers that undergo selective Michael‐type polyaddition with multithiols to from thiol‐guaiacol connectivity‐bearing polymers. The activation applies to discrete monomers and directly to lignin, enabling two‐component adhesives that ...
Dominik P. Hoch, Keven Walter, Oliver Sipura, Jana Falkenhagen, Xinyang Peng, Leon Gerndt, Hamy Nguyen, Hans G. Börner   +7 more
wiley   +1 more source

Effect of α-lipoic acid on symptoms and quality of life in patients with painful diabetic neuropathy

Journal of International Medical Research, 2018
Objective To examine the effect of α-lipoic acid on neuropathic symptoms in patients with diabetic neuropathy (DN). Methods Patients with painful DN were treated with 600 mg/day α-lipoic acid, orally, for 40 days.
Evangelos Agathos, Anastasios Tentolouris, Ioanna Eleftheriadou, Panagiota Katsaouni, Ioannis Nemtzas, Alexandra Petrou, Christina Papanikolaou, Nikolaos Tentolouris   +7 more
doaj   +1 more source

Possibilities of pharmacologic correction of cognitive disorders in conditions of experimental equivalent of multiple sclerosis.

Medičnì Perspektivi, 2015
A comparative analysis of the impact of citicoline, α-lipoic acid, nicergoline, donepezil and colloidal solution of nano-silver (CSNS) on the processes of learning and consolidation of memorable track in the test of the conditional reaction of passive ...
A. A. Nefyodov, V. Io. Mamchur
doaj   +1 more source

Translational development of crisugabalin for neuropathic pain

British Journal of Clinical Pharmacology, EarlyView.
Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João, Jilly Octoria Tagore Chan, Luísa Mendes Araújo, André Batista João, Raquel Mattos Filgueiras, Paulo César Ragazzo   +5 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Histological investigation of α-lipoic acid in the wound healing process of diabetic lesions in vivo

Acta Scientiarum: Biological Sciences
α-Lipoic acid (ALA) is a significant therapeutic agent for inflammation. Understanding the histological parameters involved in the healing process influenced by inflammatory activity is crucial for developing new technologies to treat wounds caused by ...
Guilherme Fernandes Teixeira, Vithoria Régia Teixeira Rodrigues, Andreza Gyslaynny Delmondes Saraiva, Kelvi Wilson Evaristo Miranda, Claudio Gleidiston Lima da Silva, Woneska Rodrigues Pinheiro, Luis Rafael Leite Sampaio   +6 more
doaj   +1 more source