Results 81 to 90 of about 21,573 (205)

Effect of α-lipoic acid on symptoms and quality of life in patients with painful diabetic neuropathy

Journal of International Medical Research, 2018
Objective To examine the effect of α-lipoic acid on neuropathic symptoms in patients with diabetic neuropathy (DN). Methods Patients with painful DN were treated with 600 mg/day α-lipoic acid, orally, for 40 days.
Evangelos Agathos, Anastasios Tentolouris, Ioanna Eleftheriadou, Panagiota Katsaouni, Ioannis Nemtzas, Alexandra Petrou, Christina Papanikolaou, Nikolaos Tentolouris   +7 more
doaj   +1 more source

Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies Results

Mìžnarodnij Endokrinologìčnij Žurnal, 2016
Primary hypothyroidism occurs in the general population with an incidence of 0.5–1 %, and includes congenital and acquired (due to autoimmune thyroiditis, after surgical removal of the thyroid gland or treatment with radioactive iodine) forms.
A.V. Savustyanenko
doaj   +1 more source

Glycosylation with O-linked β-N-acetylglucosamine (O-GlcNAc) induces vascular dysfunction via production of superoxide anion/reactive oxygen species [PDF]

, 2018
Overproduction of superoxide anion (•O2-) and O-linked β-N-acetylglucosamine (O-GlcNAc)-modification in the vascular system are contributors to endothelial dysfunction.
Alves-Lopes, Rhéure, Dela Justina, Vanessa, Giachini, Fernanda Regina, Lima, Victor V., Mestriner, Fabíola Leslie, Neves, Karla Bianca, Silva Miguez, Jéssica, Souza-Silva, Leonardo, Tostes, Rita C.   +8 more
core   +2 more sources

Enhanced Degradation of Vinyl Copolymers Based on Lipoic Acid

Journal of Polymer Science, Volume 63, Issue 6, Page 1345-1351, 15 March 2025.
ABSTRACT The introduction of degradable units into the backbone of commodity vinyl polymers represents a major opportunity to address the societal challenge of plastic waste and polymer recycling. Previously, we reported the facile copolymerization of α‐lipoic acid derivatives containing 1,2‐dithiolane rings with vinyl monomers leading to the ...
Yoichi Okayama, Parker Morris, Kaitlin Albanese, Sarah Olsen, Atsunori Mori, Javier Read de Alaniz, Christopher M. Bates, Craig J. Hawker   +7 more
wiley   +1 more source

Effect of α-lipoic acid on the removal of arsenic from arsenic-loaded isolated liver tissues of rat

Bangladesh Journal of Pharmacology, 2006
The patient of chronic arsenic toxicity shows oxidative stress. To overcome the oxidative stress, several antioxidants such as beta-carotene, ascorbic acid, α-tocopherol, zinc and selenium had been suggested in the treatment of chronic arsenic toxicity ...
Noor E-Tabassum
doaj  

Current experience in testing mitochondrial nutrients in disorders featuring oxidative stress and mitochondrial dysfunction: rational design of chemoprevention trials [PDF]

, 2014
An extensive number of pathologies are associated with mitochondrial dysfunction (MDF) and oxidative stress (OS). Thus, mitochondrial cofactors termed “mitochondrial nutrients” (MN), such as α-lipoic acid (ALA), Coenzyme Q10 (CoQ10), and l-carnitine ...
Castello, Giuseppe, Cordero Morales, Mario David, d'Ischia, Marco, Gadaleta, Maria Nicola, Pagano, Giovanni, Talamanca, Annita Aiello   +5 more
core  

A silver complex of hyaluronan-lipoate (SHLS12): Synthesis, characterization and biological properties [PDF]

, 2016
In this study we present a novel silver complex of hyaluronan-lipoate (SHLS12) in a gel-state form. NMR analysis, conductometry and elemental analysis demonstrated stable non-covalent interactions between silver ions and the polysaccharide-lipoate ...
Bosco, Marco, Fabbian, Matteo, Gianni, Rita, Marsich, Eleonora, Paoletti, Sergio, Picotti, Fabrizio, Sacco, Pasquale, Sechi, Alessandra, Stucchi, Luca, Trevisan, Antonia   +9 more
core   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Histological investigation of α-lipoic acid in the wound healing process of diabetic lesions in vivo

Acta Scientiarum: Biological Sciences
α-Lipoic acid (ALA) is a significant therapeutic agent for inflammation. Understanding the histological parameters involved in the healing process influenced by inflammatory activity is crucial for developing new technologies to treat wounds caused by ...
Guilherme Fernandes Teixeira, Vithoria Régia Teixeira Rodrigues, Andreza Gyslaynny Delmondes Saraiva, Kelvi Wilson Evaristo Miranda, Claudio Gleidiston Lima da Silva, Woneska Rodrigues Pinheiro, Luis Rafael Leite Sampaio   +6 more
doaj   +1 more source

Centrally formed acetaldehyde mediates ethanol-induced brain PKA activation [PDF]

, 2014
Centrally formed acetaldehyde has proven to be responsible for several psychopharmacological effects induced by ethanol. In addition, it has been suggested that the cAMP-PKA signaling transduction pathway plays an important role in the modulation of ...
Baliño, Pablo, González Aragón, Carlos Manuel, Tarragon Cros, Ernesto   +2 more
core   +1 more source