Results 171 to 180 of about 10,117 (217)
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Stability of compounded thioguanine oral suspensions
American Journal of Health-System Pharmacy, 2011PURPOSE. Updated information on the stability of compounded thioguanine oral suspensions prepared with currently available ingredients, as well as results of testing to determine if the addition of an antioxidant could extend shelf life by inhibiting formation of guanine, are presented. METHODS.
Hamidreza Montazeri, Aliabadi +4 more
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Transglycosylation Reactions of 6-Thioguanine Acyclonucleosides
Nucleosides, Nucleotides and Nucleic Acids, 20009-(2-Acetoxyethoxy)methyl-N2-acetyl-6-thoguanine (2) undergoes two different transglycosylation reactions: i) the 79 isomerization, which gives the respective 7-regioisomer (3) as the major product, ii) the 9S6 glycosyl migration, which leads to a 9,S6-disubstituted product (4). S6-Methylation completely stopped the reversibility of transglycosylation.
A, Manikowski, J, Boryski
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The Inhibition of Hemagglutinin Formation in Mice by Thioguanine
The Journal of Immunology, 1962Summary Thioguanine at a dose of 2.5 mg/kg was shown to be an effective inhibitor of the primary hemagglutinin response in both mice and rabbits. Similarly, 6-MP at a level of 15 mg/kg, prevented the formation of sheep cell hemagglutinins in rabbits. In mice, evidence of suppression was obtained with doses of 2.5 mg/kg begun on the first
A W, FRISCH, G H, DAVIES, V, MILSTEIN
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Correction: Dosage of Thioguanine
Annals of Internal Medicine, 1975Excerpt To the editor: In the letter "Hyperphosphatemia and Hypocalcemia in Myeloproliferative Disorder" (Ann Intern Med81:119-120, 1974), the dose of thioguanine was published as 25 mg/kg body wei...
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Thioguanine, Mercaptopurine: Their Analogs and Nucleosides as Antimetabolites
Current Pharmaceutical Design, 20036-Mercaptopurine (6MP) and 6-thioguanine (6TG) are analogs of the natural purines: hypoxanthine and guanine. Both mercaptopurine and thioguanine are substrates for hypoxanthine-guanine phosphoribosyltransferase and are converted into the ribonucleotides 6-thioguanosine monophosphate (6-thioGMP) and 6-thioinosine monophosphate (T-IMP) respectively.
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Carcinogenesis, 1981
The availability of a number of well characterised mammalian cell mutants which revert at measurable frequencies when exposed to specific chemical mutagens would considerably aid analysis of mechanisms of mutagenesis in mammalian cells, might ultimately provide the mammalian cell equivalent of the "Ames' tester strains and could aid the understanding ...
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The availability of a number of well characterised mammalian cell mutants which revert at measurable frequencies when exposed to specific chemical mutagens would considerably aid analysis of mechanisms of mutagenesis in mammalian cells, might ultimately provide the mammalian cell equivalent of the "Ames' tester strains and could aid the understanding ...
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