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Asymmetric Hydrogen Atom Transfer. [PDF]

open access: yesACS Catal
Feng AG   +3 more
europepmc   +1 more source

Modulating IDO1 and TDO Inhibition Through Structural Modification of Diaryl Hydroxylamines. [PDF]

open access: yesChemMedChem
Foscolos AS   +8 more
europepmc   +1 more source
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Thiols, Thiol Depletion, and Thermosensitivity

Radiation Research, 1983
Hyperthermia sensitization or tolerance is subject to cellular events that may occur at membrane, nuclear, and cytoplasmic sites. We have studied the effects of elevated temperatures on the oxidative-reductive state of the cell by measuring and altering glutathione (GSH) concentrations. GSH plays a pivotal role in maintaining the overall cellular redox
J B, Mitchell, A, Russo
openaire   +2 more sources

Thiols, gold-thiols, zinc-thiols and the redox state of hemoglobin

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1993
The beta subunit of human hemoglobin can be oxidized site-specifically through beta-Cys-93 by Cu(II)(His)2. A series of thiol ligands, gold thiols and zinc(II) inhibit this oxidation. The thiol inhibitors formed a transient ternary intermediate involving Cu(I) with consequent inhibition of electron transfer from the Fe(II)-heme. The intermediate led to
S, Potuznik   +3 more
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