Results 41 to 50 of about 113,120 (285)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Fast and Highly Efficient Solid State Oxidation of Thiols
Molecules, 2007 A fast and efficient solid state method for the chemoselective room temperature oxidative coupling of thiols to afford their corresponding disulfides using inexpensive and readily available moist sodiumperiodate as the reagent is described.
Nasrin Haghighat +3 more
doaj +1 more source
The nitrite anion: the key intermediate in alkyl nitrates degradative mechanism. [PDF]
, 2007 Alkyl nitrates, _in vivo_, are metabolized to yield nitric oxide, and thiol groups are considered necessary cofactors. This statement is based on studies that underline how these species potentiate hemodynamic responsiveness to nitrates in patients with ...
Loris Grossi
core +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
ORIGINAL ARTICLE: Protein Thiols in Essential Hypertension Patients [PDF]
Journal of Krishna Institute of Medical Sciences University, 2012 Background: Essential hypertension is one of the most prevalent diseases of the world and is an unequivocal risk factor for cardiovascular morbidity and mortality.
Jagadish. B. Ingin +2 more
doaj
Molecules, 2019 A new cyan fluorescent probe, MIPY-DNBS, using an imidazo[1,5-α]pyridine derivative as the fluorophore and 2,4-dinitrobenzensufonate as the recognition site for the selective detection of thiols (Cys, GSH, and Hcy), was designed and synthesized ...
Song Chen +4 more
doaj +1 more source
UV-Induced Nanoparticles-Formation, Properties and Their Potential Role in Origin of Life
Nanomaterials, 2020 Inorganic nanoparticles might have played a vital role in the transition from inorganic chemistry to self-sustaining living systems. Such transition may have been triggered or controlled by processes requiring not only versatile catalysts but also ...
Lukas Nejdl +11 more
doaj +1 more source
Exploiting Thiol Modifications
PLoS Biology, 2004 Molecular oxygen may be necessary for life but with its beneficial properties comes formation of potentially toxic reactive oxygen species.
Patricia J Kiley, Gisela Storz
openaire +4 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Thermal Stability of Self-Assembled Monolayers of n-Hexanethiol on Au(111)-(1 × 1) and Au(001)-(1 × 1) [PDF]
, 2017 Thermal desorption in an ultrahigh vacuum of n-hexanethiol (C6T) self-assembled monolayers (SAMs) prepared from ethanolic solutions on Au(111) and Au(001) unreconstructed surfaces was investigated by X-ray photoelectron spectroscopy.
Afeefy H. Y. +5 more
core +2 more sources