Transition-metal-catalyzed synthesis of phenols and aryl thiols
Phenols and aryl thiols are fundamental building blocks in organic synthesis and final products with interesting biological activities. Over the past decades, substantial progress has been made in transition-metal-catalyzed coupling reactions, which ...
Yajun Liu, Shasha Liu, Yan Xiao
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Introduction. Pemphigus vulgaris (PV) is a life-threatening disease of the skin and mucous membranes that is associated with IgG antibodies that target several types of keratinocyte antigens and cause epidermal lysis (acantholysis) via intracellular ...
V. A. Litvinov, H. I. Makurina
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Effects of storage conditions on thiol disulfide homeostasis
We planned this study to research the effect of freeze-thaw number and storage temperatures on the tests of thiol-disulfide homeostasis. Dynamic thiol-disulfide homeostasis has a crucial role in antioxidant defense reactions.
Ahmet Rifat Balik +5 more
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Rapid and Thiol-Specific High-Throughput Assay for Simultaneous Relative Quantification of Total Thiols, Protein Thiols, and Nonprotein Thiols in Cells [PDF]
Thiol groups in biological molecules play a significant role in various physiological functions and pathological conditions. Thiols are divided into two major groups: protein thiols and nonprotein thiols. Numerous methods have been reported for thiol assays.
Yang, Yang, Guan, Xiangming
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Scientific Opinion on Flavouring Group Evaluation 91, Revision 2 (FGE.91Rev2): Consideration of simple aliphatic and aromatic sulphides and thiols evaluated by the JECFA (53rd and 68th meetings) structurally related to aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups evaluated by EFSA in FGE.08Rev5 (2012) [PDF]
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
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Synthesis and crystal structure of (E)-1,2-bis[2-(methylsulfanyl)phenyl]diazene
The title compound, C14H14N2S2, was obtained by transmetallation of 2,2′-bis(trimethylstannyl)azobenzene with methyl lithium, and subsequent quenching with dimethyl disulfide.
Jonas Hoffmann +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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ORIGINAL ARTICLE: Protein Thiols in Essential Hypertension Patients [PDF]
Background: Essential hypertension is one of the most prevalent diseases of the world and is an unequivocal risk factor for cardiovascular morbidity and mortality.
Jagadish. B. Ingin +2 more
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Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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Fast and Highly Efficient Solid State Oxidation of Thiols
A fast and efficient solid state method for the chemoselective room temperature oxidative coupling of thiols to afford their corresponding disulfides using inexpensive and readily available moist sodiumperiodate as the reagent is described.
Nasrin Haghighat +3 more
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