Results 21 to 30 of about 8,057 (210)

ESI-MS fragmentation pathways of some 1,2,4-triazole-3-thiones, the intermediate compounds in the synthesis of active pharmaceutical ingredients

Журнал органічної та фармацевтичної хімії, 2020
Aim. To determine the fragmentation pathways of eight 1,2,4-triazole-3-thiones, which are intermediate products in the synthesis of active pharmaceutical ingredients of potential and registered pharmaceutical formulations. Results and discussion. HPLC-
Borys O. Varynskyi, Andriy G. Kaplaushenko   +1 more
doaj   +1 more source

Multicomponent Synthesis of 3,6-Dihydro-2H-1,3-thiazine-2-thiones

Molecules, 2012
Non-fused 3,6-dihydro-2H-1,3-thiazine-2-thiones constitute a so far rather unexplored class of compounds, with the latest report dating back more than two decades.
Frans J. J. de Kanter, Eelco Ruijter, Romano V. A. Orru, Madeleine Helliwell, Elwin Janssen, Marten L. Ploeger, Art Kruithof   +6 more
doaj   +1 more source

Synthesis and biological evaluation of 1,2,4-triazoles and 1,3,4-oxadiazoles derivatives linked to 1,4-dihydropyridines scaffold

Acta Chimica Slovenica, 2017
A series of diethyl-2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate derivative coupled to 1,3,4-oxadiazole-5-thiones and 1,2,4-triazole-5-thiones moieties at C2,C6 positions of 1,4-dihydropyridine ring system was prepared.
Maghsoud Ziaie, Karim Akbaridilmaghani, Amir Tukmechi   +2 more
doaj   +1 more source

Synthesis and assessment of the cytotoxic effect of some of 1,4-dihydropyridine derivatives which contain azole moiety [PDF]

Journal of the Serbian Chemical Society, 2021
A number of 1,4-dihydropyridine derivatives (9a–d, 10a–d and 11a–d) were designed and synthesized by the reaction of 1,3,4-oxadiazole-5-thiones and 1,2,4-triazole-5-thiones to 2,6-dibromomethyl-3,5-diethoxycarbonyl-4-(3- -nitrophenyl)-1,4-dihydropyridine.
Ghoorbannejad Saeed, Akbari Dilmaghani Karim, Nikoo Abbas   +2 more
doaj   +1 more source

1.3.4.2-Thiadiazaphospholin-2-thione / 1,3,4,2-Thiadiazaphospholine-2-thiones

Zeitschrift für Naturforschung B, 1979
Abstract Perthiophosphonic anhydrides (1) and phos-phorus(V) sulfide react with benzo-phenylhydra-zonoyl chloride (2) eliminating HCl and yielding the title compounds 3 and 4, which formally are cycloadducts of the monomeric units RPS2 and P2S5, respectively, and diphenyl nitrilimine.
Werner Zeiß, Alfred Schmidpeter
openaire   +1 more source

A New Convenient Synthesis of 5-Acyl-1,2,3,4-tetrahydropyrimidine-2-thiones/ones

Molecules, 1998
An efficient one-pot synthesis of 5-acyl-1,2,3,4-tetrahydropyrimidine-2-thiones/ones is described. The synthesis is based on the reaction of readily available α-tosyl substituted thioureas or ureas with enolates of β-oxoesters or 1,3-dicarbonyl ...
Aleksei Yu. Kuznetsov, Natalie V. Sivova, Ekaterina A. Kishko, Anatoly D. Shutalev   +3 more
doaj   +1 more source

1-(4-Chloro­phen­yl)-4,4,6-trimethyl-3,4-dihydro­pyrimidine-2(1H)-thione [PDF]

, 2010
The dihydro­pyrimidine ring of the title compound, C13H15ClN2S, adopts an envelope conformation with five almost coplanar atoms (r.m.s. deviation = 0.054 Å) and the C atom bearing the two methyl substituents deviating from this plane by 0.441 (2) Å.
Aamer Saeed, Michael Bolte, Alam, Blessing, Kappe, Leite, Rovnyak, Sheldrick, Spek, Sriram, Swamy, Yamin   +11 more
core   +1 more source

Domino Polymerization for the Synthesis of Reductively Degradable Poly(disulfide)s With Arbitrary Side‐Chain Structures

Angewandte Chemie, EarlyView.
We developed a novel domino polymerization to synthesize reductively degradable poly(disulfide)s with tunable side chains. A novel monomer bearing thiolactone and pyridyl disulfide groups reacts with various amines, enabling continuous ring‐opening and disulfide exchange.
Yukiya Kitayama, Ryodai Sakamoto, Atsushi Harada   +2 more
wiley   +2 more sources

Synthesis and Antimicrobial Activity of New 5-(2-Thienyl)-1,2,4-triazoles and 5-(2-Thienyl)-1,3,4-oxadiazoles and Related Derivatives

Molecules, 2010
New 5-(2-thienyl)-1,2,4-triazoles and 5-(2-thienyl)-1,3,4-oxadiazoles namely, N-[3-mercapto-5-(2-thienyl)-1,2,4-triazol-4-yl]-N'-arylthioureas 4a–e, 2-arylamino-5-(2-thienyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles 5a–e, 3-arylaminomethyl-5-(2-thienyl ...
Mohamed A. Al-Omar
doaj   +1 more source

Microwave-Assisted Improved Synthesis of Oxazolidin-2-ones, Oxazolidine-2-thiones and Thiazolidine-2-thione Chiral Auxiliaries

Molecules, 2011
A microwave assisted method for the synthesis of some typical 4-substituted oxazolidinone chiral auxiliaries used in asymmetric synthesis is reported in this work.
Mario Ordóñez, Rosmarbel Morales-Nava, Mario Fernández-Zertuche   +2 more
doaj   +1 more source