Results 1 to 10 of about 1,367 (120)

Nucleoside cyclic 3′,5′-phosphorothioates with purine and pyrimidine scaffolds. A chemical minireview

open access: yesEuropean Journal of Medicinal Chemistry Reports, 2022
The common nucleobases purine (adenine and guanine) and pyrimidine (cytosine, uracil and thymine) in naturally occurring nucleosides and their 3′,5′-cyclic phosphates are β-bonded to the anomeric carbon (C1′) of d-ribose or its 2′-deoxy congener.
Kjell Undheim
doaj   +1 more source

Artificial Specific Binders Directly Recovered from Chemically Modified Nucleic Acid Libraries

open access: yesJournal of Nucleic Acids, Volume 2012, Issue 1, 2012., 2012
Specific binders comprised of nucleic acids, that is, RNA/DNA aptamers, are attractive functional biopolymers owing to their potential broad application in medicine, food hygiene, environmental analysis, and biological research. Despite the large number of reports on selection of natural DNA/RNA aptamers, there are not many examples of direct screening
Yuuya Kasahara   +2 more
wiley   +1 more source

Chemical Synthesis of Modified RNA

open access: yesAngewandte Chemie International Edition, Volume 63, Issue 22, May 27, 2024.
Recent developments in the field of chemical RNA synthesis are discussed, starting with protection concepts, followed by selected nucleoside modifications that are challenging to incorporate into RNA. Comments on the chemical synthesis of 5′‐capped mRNAs, the enzymatic ligation of synthetic RNA, and RNA‐catalyzed RNA modifications using cofactors that ...
Laurin Flemmich   +2 more
wiley   +1 more source

Electrosynthesis of Artificial Peptides and Nucleosides via the Nitromethane–Lithium Perchlorate Electrolyte System: A Review

open access: yesChemElectroChem, Volume 11, Issue 1, January 2, 2024.
Electrosynthesis of artificial peptides and nucleosides: Electrosynthetic methodologies have frequently found application in chemical production processes. In the past few decades, the MeNO2‐LiClO4 electrolyte system has significantly enhanced the reactivity of cationic species in oxidative electrochemical reactions.
Kazuhiro Okamoto, Kazuhiro Chiba
wiley   +1 more source

Sulfur incorporation into biomolecules: recent advances. [PDF]

open access: yesCrit Rev Biochem Mol Biol, 2022
Chatterjee S, Hausinger RP.
europepmc   +1 more source

Home - About - Disclaimer - Privacy