Computing Network of Diseases and Pharmacological Entities through the Integration of Distributed Literature Mining and Ontology Mapping [PDF]
, 2011 The proliferation of -omics (such as, Genomics, Proteomics) and -ology (such as, System Biology, Cell Biology, Pharmacology) have spawned new frontiers of research in drug discovery and personalized medicine.
Faisal, Fazle Elahi
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Sulfur incorporation into biomolecules: recent advances. [PDF]
Crit Rev Biochem Mol Biol, 2022 Chatterjee S, Hausinger RP.
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Site Saturation Mutagenesis of Residue 71 in β-Lactamase [PDF]
, 1986 A method was developed to "saturate" a particular residue in a protein with all possible amino acid substitutions. The method essentially involves introducing into the gene at the codon for the residue of interest a mixture of nucleotides: A, C, G, and T
Schultz, Steve Chester
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Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets. [PDF]
Platelets, 2022 Dangelmaier C, Kunapuli SP.
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Characterization of SufS and SufE of Suf Pathway for FE-S Cluster Assembly in Escherichia Coli [PDF]
, 2017 Fe-S clusters are one major type of the sulfur-containing cofactors, which conduct essential functions in organisms. The Suf pathway is one of the three main pathways for the biosynthesis of Fe-S clusters. In E.
Dong, Guangchao
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"2'-deoxy-6-thioguanosine :synthesis of monomer, oligomers and long DNA, and their binding with metal ions [PDF]
, 2013 PhD ThesisThe formation of one-dimensional (1D) coordination polymers using thiolated DNA nucleosides and nucleotides with transition metals was investigated. 2’-Deoxy-6- 1 13 thioguanosine was successfully synthesised and characterized by H-NMR,
Hribesh, Samira
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Functional and structural characterization of the mevalonate diphosphate decarboxylase and the isopentenyl diphosphate isomerase from Enterococcus faecalis [PDF]
, 2016 Enterococcus faecalis causes a diverse range of nosocomial infections (in wounds, the gastrointestinal tract, the blood stream and the endocardium), and multidrug-resistant strains have become a serious issue across countries.
Chen, Chun-Liang
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Functional and structural characterization of Aquifex aeolicus sulfide:quinone oxidoreductase [PDF]
, 2010 This work presents the first complete structure of the membrane protein sulfide:quinone oxidoreductase (SQR), obtained by X-ray crystallography. Its description is complemented by the results of biochemical and functional experiments. SQRs are ubiquitous
Marcia, Marco
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Small Molecule Control of Morpholino Antisense Oligonucleotide Function through Staudinger Reduction. [PDF]
J Am Chem Soc, 2021 Darrah K +5 more
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Aptamer Sensors for Drugs of Abuse and Medical Biomarkers: Design, Engineering and Application in Complex Samples [PDF]
, 2018 Aptamers are short oligonucleotide sequences (DNA or RNA) capable of high affinity and specific binding to a molecule or a family of molecules. Aptamers are lower in cost and exhibit higher reproducibility when compared to antibodies and thus are well ...
Roncancio, Daniel
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