Absolute configuration of cytotoxic anthraquinones from a Brazilian cave soil-derived fungus, Aspergillus sp. SDC28. [PDF]
Gubiani JR+10 more
europepmc +1 more source
The Development and Evaluation of Novel Reagents for Pre-Targeted Radioimmunotherapy [PDF]
PhDIn a pretargeting radioimmunotherapy system, monoclonal antibodies (MAbs) derivatised with a high affinity streptavidin receptor are used in a localisation step.
Hainsworth, James Edward Scott
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The upregulated expression of RFC4 and GMPS mediated by DNA copy number alteration is associated with the early diagnosis and immune escape of ESCC based on a bioinformatic analysis. [PDF]
Wang J+6 more
europepmc +1 more source
Some studies on the low molecular weight RNA components of mammalian cells [PDF]
Until recently, RNA was considered to belong to one of three categories; transfer RNA(tRNA), ribosomal RNA or messenger RNA. In addition however, the development of more sophisticated analytical techniques such as polyacrylamide gel electrophoresis ...
Clason, Alexander E
core
Cytotoxicity of Thiopurine Drugs in Patients with Inflammatory Bowel Disease. [PDF]
Zakerska-Banaszak O+5 more
europepmc +1 more source
Kinetic studies on the fidelity of DNA replication involving DNA templates containing O6-methylguanine [PDF]
Production by N-nitroso compounds of O6-alkylguanine (O6-alkylG) in DNA directs the misincorporation of thymine during DNA replication, leading to G:C to A:T transition mutations, despite the fact that DNA containing O6>alkylG:T base-pairs is less ...
Tan, Hwee Boon
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Chemical RNA Cross-Linking: Mechanisms, Computational Analysis, and Biological Applications. [PDF]
Velema WA, Lu Z.
europepmc +1 more source
Études Structurales par Résonance Magnétique Nucléaire (RMN) du Site Actif du Ribozyme VS de Neurospora [PDF]
Nous étudions le ribozyme VS de Neurospora, en tant que système modèle, pour augmenter nos connaissances sur la relation entre la structure et la fonction chez les ARNs, ainsi que pour mieux comprendre le mécanisme de clivage de ce ribozyme.
Desjardins-Séguin, Geneviève
core +1 more source
Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters. [PDF]
Miller SR+7 more
europepmc +1 more source
Sviluppo di strategie farmacologiche per la personalizzazione della terapia della leucemia linfoblastica acuta nel bambino [PDF]
2012/2013L'attività dell'enzima tiopurina-S-metil transferasi (TPMT) è un determinante importante di eventi avversi severi durante il trattamento della leucemia linfoblastica acuta (LLA) con l'antimetabolita mercaptopurina.
Londero, Margherita
core +1 more source