Results 61 to 70 of about 16,204 (217)

Chinese Society of Pediatric Anesthesiology Guideline for Pediatric Sedation (2025)

open access: yesPediatric Anesthesia, Volume 36, Issue 7, Page 850-871, July 2026.
ABSTRACT Background With the increasing variety of pediatric diagnostic procedures, a growing number of children require sedation for diagnostic examinations. Appropriate sedation protocols guarantee the safety of children during sedation and improve its efficiency.
Xingrong Song   +39 more
wiley   +1 more source

Adrenoceptor mechanism involved in thiopental-epinephrine-induced arrhythmias in dogs

open access: yes, 1993
The authors investigated the role of alpha 1- and beta-adrenoceptors on induction of ventricular arrhythmias during thiopental anesthesia in dogs and compared with that during halothane anesthesia.
M. Kuro   +5 more
core   +1 more source

Thiopental enhances human platelet aggregation by increasing arachidonic acid release

open access: yes, 2001
Conflicting results have been reported regarding the effect of thiopental on aggregation and cytosolic calcium levels in platelets. The present study attempted to clarify these phenomena.
Masami Sato   +8 more
core   +1 more source

Comparison of Ketamine-Propofol and Ketamine-Thiopental on Bispectral Index Values during Monitored Anesthesia Care (MAC) in Minor Traumatic Orthopedic Surgery; A Randomized, Double-Blind, Clinical Trial [PDF]

open access: yesBulletin of Emergency and Trauma, 2019
Objective: To compare the effects of ketamine-propofol and ketamine-thiopental on bispectral index values during monitored anesthesia care in minor orthopedic surgeries.Methods: This randomized double-blind clinical trial was performed on 90 patients ...
Afsaneh Nowroozi   +3 more
doaj   +1 more source

Sedation Therapy in Intensive Care Units: Harnessing the Power of Antioxidants to Combat Oxidative Stress

open access: yesBiomedicines, 2023
In critically ill patients requiring intensive care, increased oxidative stress plays an important role in pathogenesis. Sedatives are widely used for sedation in many of these patients. Some sedatives are known antioxidants.
Gen Inoue   +12 more
doaj   +1 more source

Transcriptomic analysis reveals lipid metabolism and macrophage involvement associated with nintedanib treatment in a rat bleomycin model

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 12, Page 3395-3408, June 2026.
In this study, nintedanib reduced lung fibrosis in a rat double‐hit bleomycin‐induced model. Transcriptomic analysis revealed two key gene signatures related to the effect of the molecule: one involving mesenchymal cells affecting known fibrotic pathways and another linking mainly macrophages to lipid metabolism.
Martina Bonatti   +14 more
wiley   +1 more source

Rapid sevoflurane induction compared with thiopental

open access: yes, 2004
To examine whether the speed of induction of anesthesia with sevoflurane/nitrous oxide (N 2O) utilizing a 10-second vital capacity rapid inhalation induction (VCRII) followed by tidal breathing was similar or faster than cautious intravenous (IV ...
Christina M Matadial   +13 more
core   +1 more source

A comparison of propofol and thiopentone for electroconvulsive therapy

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2012
Objectives: To compare propofol and thiopental as anesthetic agents for electroconvulsive therapy (ECT) with respect to seizure duration, stimulus charge, and clinical effects.
Alok Kumar   +2 more
doaj   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, Volume 38, Issue 26, 8 May 2026.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Estudo da ação inflamatória aguda do tiopental intraperitoneal em ratos Acute inflammatory action of tiopental intraperitoneal in rats

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005
Determinou-se a ação inflamatória aguda do tiopental intraperitoneal (IP) utilizando-se 72 ratos, divididos em grupo-tratado (40mg/kg de tiopental a 2,5% IP) e grupo-controle (0,25ml de solução fisiológica IP).
A.B. Carregaro   +2 more
doaj   +1 more source

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