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Thiophene Synthesis

2022
Thiophenes are sulfur-containing aromatic heterocycles, the simple derivatives of which are stable liquids. Unlike their nitrogen-containing analogues, thiophene-containing compounds rarely occur in plants and have no role in the metabolism of animals.
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Flexible Routes to Thiophenes

Organic Letters, 2013
Three convergent routes to thiophenes are described, hinging on the radical addition of α-xanthyl ketones to ethyl vinyl sulfide or to vinyl pivalate. The latter route ultimately proved to be the most versatile and efficient (61-94%).
Jullien, Hélène   +3 more
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Radiation-Driven Destruction of Thiophene and Methyl-Substituted Thiophenes

Astrobiology
Thiophene and two derivatives (2-methylthiophene and 3-methylthiophene) have been detected on the surface of Mars with the Sample Analysis at Mars instrument suite onboard NASA's Curiosity rover. Thiophene could serve as a secondary chemical biosignature since the secondary biosynthesis of thiophene is considered an important production pathway ...
Patrick D. Tribbett   +4 more
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Bis(ferrocenylsilyl)thiophenes and ferrocenylene(silylene)thiophene oligomers

Polyhedron, 2000
Abstract The reaction between 1,1′-dilithioferrocene and 2,5-bis(chlorodimethylsilyl)thiophene ( I ), leads to a series of cyclic oligomers of basic formulation [Fc-SiMe 2 -TH-SiMe 2 ] n ( II ); Fc=(η 5 -C 5 H 4 ) 2 Fe, TH=C 4 H 2 S. The material n =2, IIa , has been completely characterized by spectroscopic and single crystal X-ray diffraction.
Keith H. Pannell   +3 more
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Thiophene chemistry—XX

Tetrahedron, 1970
E.B. Pedersen, S.-O. Lawesson
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Chapter 5 Thiophenes and benzo[b]thiophenes

2007
Publisher Summary Thiophene is a useful template for four-carbon homologation via reduction, as well as a bioisostere of the benzene ring and other heterocycles in medicinal chemistry. Thiophene is a π-electron-excessive heterocycle. It favors electrophilic substitution, which, similar to metalation, takes place preferably at the α-positions due to
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Anti-resonance features of destructive quantum interference in single-molecule thiophene junctions achieved by electrochemical gating

Nature Materials, 2019
Jie Bai   +16 more
semanticscholar   +1 more source

An overview of benzo[b]thiophene-based medicinal chemistry.

European journal of medicinal chemistry, 2017
R. Keri   +5 more
semanticscholar   +1 more source

Thiophen

Fresenius' Zeitschrift f�r Analytische Chemie, 1955
H. Freytag, Irmgard Schweitzer, J. Rasch
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Supramolecular Thiophene Nanosheets

Angewandte Chemie, 2013
Zheng, Y.   +8 more
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