Results 251 to 260 of about 38,014 (298)

Fused thiophene derivatives as MEK inhibitors

Bioorganic & Medicinal Chemistry Letters, 2012
A number of novel fused thiophene derivatives have been prepared and identified as potent inhibitors of MEK. The SAR data of selected examples and the in vivo profiling of compound 13 h demonstrates the functional activity of this class of compounds in HT-29 PK/PD models.
Victoria E, Laing, Daniel C, Brookings, Rachel J, Carbery, Jose Gascon, Simorte, Martin C, Hutchings, Barry J, Langham, Martin A, Lowe, Rodger A, Allen, Joanne R, Fetterman, James, Turner, Christoph, Meier, Jeff, Kennedy, Mark, Merriman   +12 more
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Reaction of Dicarbomethoxycarbene with Thiophene Derivatives

The Journal of Organic Chemistry, 2009
Photolysis of derivatives of dimethylmalonate thiophene-S,C-ylide provides dicarbomethoxycarbene, which can react with thiophene to form dimethyl (2-thienyl)malonate. By generation of dicarbomethoxycarbene from the dibenzothiophene-based ylide in neat thiophene, it is shown that the thienylmalonate is not a product of rearrangement of the thiophene ...
Jenks, William, Heying, Melanie, Stoffregen, Stacey, Rockafellow, Erin   +3 more
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Thin-layer chromatography of thiophene derivatives

Journal of Chromatography A, 1962
Abstract A method for the qualitative separation of various thiophene derivatives by means of thin-layer chromatography is described.
R F, CURTIS, G T, PHILLIPS
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Organic laser based on thiophene derivatives

Synthetic Metals, 2003
Abstract Laser action is obtained from two different neat films of electroluminescent oligothiophenes. The emissions are tunable, from the yellow to the red, on wavelength ranges up to 37 nm centered around 600 nm, in single-mode with a TEM 00 beam quality. The lasers exhibit low pump thresholds and efficiencies up to 1.7%.
M. ZAVELANIROSSI, G. LANZANI, ANNI, Marco, GIGLI, Giuseppe, CINGOLANI, Roberto, L. FAVARETTO, G. BARBARELLA   +6 more
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Benzo[b]thiophene derivatives. VIII. Benzo[b]thiophene‐3‐earboxaldehyde and derivatives

Journal of Heterocyclic Chemistry, 1966
AbstractA procedure for the preparation of benzo[b]thiophene‐3‐carboxaldehyde from 3‐methyl‐benzo[b]thiophene is reported. This aldehyde behaves as a typical reactive aromatic aldehyde with respect to oxidation, reduction, the mixed Cannizzaro reaction, reductive amination and acyloin and other condensation reactions.
E. Campaigne, E. S. Neiss
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Regiocontrolled synthesis of poly(thiophene) derivatives: EL devices utilizing chiral poly(thiophene) derivatives

Synthetic Metals, 2001
We synthesized an optically active and regioregular poly(3-substituted thiophene), head-to-tail poly(3-[2-((S)-2-methylbutoxy)ethyl]thiophene (HT-P(S)MBET), according to a modified Rieke method. The HT-P(S)MBET was an optically active polymer with the head-to-tail linkage of 94 %. HT-P(S)MBET films showed longer maximum absorption wavelengths and lower
T. Endo, M. Rikukawa, K. Sanui
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ChemInform Abstract: Cyclohepta[b]thiophene Derivatives. Part 4. Dehydrogenation of Cyclohepta[b]thiophene and Cyclohepta[c]thiophene Derivatives.

ChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Sikha Lahiri, P. K. Sen
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Functional derivatives of thiophene

Chemistry of Heterocyclic Compounds, 1975
V. I. Shvedov, V. K. Vasil'eva, I. A. Kharizomenova, A. N. Grinev   +3 more
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Novel Ferrocene-Containing Thiophene Derivatives

Doklady Chemistry, 2019
A new 2-amino-4-ferrocenylthiophene-3-carbonitrile has been obtained by Gewald reaction, the compound has been converted into Schiff bases as precursors for new optoelectronic and magnetic materials. The structure of the prepared compounds has been established by elemental analysis, IR spectroscopy, and 1H NMR.
E. N. Rodlovskaya, V. A. Vasnev
openaire   +1 more source

Functional derivatives of thiophene

Chemistry of Heterocyclic Compounds, 1974
V. I. Shvedov, I. A. Kharizomenova, A. N. Grinev   +2 more
openaire   +1 more source