Results 1 to 10 of about 8,870 (277)

Synthesis and Antimicrobial Studies of a New Series of Bis-Heterocycles [PDF]

E-Journal of Chemistry, 2008
Series of novel bis-heterocycles bearing isoxazoline and imidazole moieties have been synthesized via 1,3-dipolarcycloaddition reactions. 1HNMR, 13CNMR, IR and elemental analyses characterized the newly synthesized compounds.
B. Jayashankara, K.M. Lokanatha Rai
doaj   +7 more sources

Synthesis of bis-Heterocyclic Derivatives of Thiohydantoin

INEOS OPEN, 2021
The possibility of structural modification of thiohydantoin derivatives via amidoalkylation under the action of a range of cyclic hemiamidals is demonstrated. The suggested approach provides, in particular, unsymmetrical nitrogen-containing bis-heterocyclic systems with pharmacologically relevant groups that are difficult to obtain by other methods.
O. N. Gorunova, N. A. Bystrova, K. A. Kochetkov   +2 more
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Efficient Synthesis of 4,8-Dibromo Derivative of Strong Electron-Deficient Benzo[1,2-d:4,5-d’]bis([1,2,3]thiadiazole) and Its S_NAr and Cross-Coupling Reactions

Molecules, 2022
An efficient synthesis of hydrolytically and thermally stable 4,8-dibromobenzo[1,2-d:4,5-d’]bis([1,2,3]thiadiazole) by the bromination of its parent heterocycle is reported.
Timofey N. Chmovzh, Daria A. Alekhina, Timofey A. Kudryashev, Oleg A. Rakitin   +3 more
doaj   +1 more source

One-pot multi-component synthesis of new bis-pyridopyrimidine and bis-pyrimidoquinolone derivatives

Heliyon, 2020
A variety of bis-heterocycles such as bis(pyrimido[4,5-b]quinolone), bis(chromeno[3′,4':5,6]pyrido[2,3-d]pyrimidine), bis(pyrido[2,3-d:6,5-d']dipyrimidine), and bis(benzo[g]pyrimido[4,5-b]quinolone) derivatives were synthesized via one-pot, multi ...
Milad Masoumi, Mohammad Bayat, Fahimeh Sadat Hosseini   +2 more
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Benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole)-4-carbonitrile

Molbank, 2023
Electron-withdrawing heterocyclic units are found in most organic optoelectronic materials. Benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole) is an interesting new heterocyclic system, the chemical properties of which are much less studied than other fused ...
Timofey N. Chmovzh, Timofey A. Kudryashev, Karim S. Gaisin, Oleg A. Rakitin   +3 more
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Combinatorial Libraries of Bis-heterocyclic Compounds with Skeletal Diversity [PDF]

Journal of Combinatorial Chemistry, 2008
Combinatorial solid-phase synthesis of bis-heterocyclic compounds, characterized by the presence of two heterocyclic cores connected by a spacer of variable length/structure, provided structurally heterogeneous libraries with skeletal diversity. Both heterocyclic rings were assembled on resin in a combinatorial fashion.
Miroslav, Soural, Isabelle, Bouillon, Viktor, Krchnák   +2 more
openaire   +2 more sources

One-Pot Synthesis of Tetrazole–Triazole Bis-Heterocycles via Ugi–Azide Reaction

Chemistry Proceedings, 2023
Bioisosteres of amide bonds such as 4,5-disubstituted-1,2,3-triazoles (4,5-DS-1,2,3-Ts) and 1,5-disubstituted tetrazoles (1,5-DST) are present in compounds with important biological activities like those that are antineoplastic, antibacterial, antifungal,
Fidel Rodriguez-Lopez, Carlos Zárate-Hernández, Manuel A. Rentería-Gómez, Rocío Gámez-Montaño   +3 more
doaj   +1 more source

Synthesis of Polyheterocyclic Dimers Containing Restricted and Constrained Peptidomimetics via IMCR-Based Domino/Double CuAAC Click Strategy

Molecules, 2020
A novel strategy via the triple process (multicomponent reactions (MCR)-domino)/tandem was developed for the synthesis of restricted and constrained bis-1,2,3-triazole-linked pyrrolo[3,4-b]pyridine peptidomimetics dimers in overall yields of 20–55%. This
Shrikant G. Pharande, Manuel A. Rentería-Gómez, Rocío Gámez-Montaño   +2 more
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Crystal structure of poly[diaqua(μ2-benzene-1,4-dicarboxylato-κ2O1:O4)(μ2-benzene-1,4-dicarboxylato-κ4O1,O1′:O4,O4′)bis(μ2-3,3′,5,5′-tetramethyl-4,4′-bipyrazole-κ2N:N′)dinickel(II)]

Acta Crystallographica Section E: Crystallographic Communications, 2015
The asymmetric unit of the polymeric title compound, [Ni(C8H4O4)(C10H14N4)(H2O)]n, contains one Ni2+ cation, one coordinating water molecule, one 3,3′,5,5′-tetramethyl-4,4′-bipyrazole ligand and half each of two benzene-1,4-dicarboxylate anions, the ...
Chao Wu, Peng Cao
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Malonates in Cyclocondensation Reactions

Molecules, 2001
The use of malonates such as diethyl malonates 9, (chlorocarbonyl)ketenes 15 and bis(2,4,6-trichlorophenyl) malonates 18 as reagents for cyclocondensation with 1,3-dinucleophiles to give six-membered heterocycles is described.
Thomas Kappe, Peter Roschger, Gerhard Hojas, El-Sayed Badawey, Wolfgang Stadlbauer   +4 more
doaj   +1 more source