Synthesis, Structural Elucidation and Bioassay of Morpholine/Thiomorpholine and Piperidine Containing Oxazoles [PDF]
, 2019 The series of novel oxazole derivatives (3-4) have been synthesized. All the entitles compounds were characterized by IR, 1H, 13C NMR, mass spectra. All the lead compounds were tested for antimicrobial activity.
Bakthavatchala Reddy, N. +3 more
core +2 more sources
Synthesis of Thieno[2,3-b]thiophene Containing Bis-Heterocycles-Novel Pharmacophores [PDF]
International Journal of Molecular Sciences, 2013 Thioenethiophene derivatives represent an important class of compounds with diverse biological activities. We describe here the synthesis of a new series of thieno[2,3-b]thiophene containing bis-heterocyclic compounds 3–7. All the compounds were evaluated for their in vitro antioxidant potential, α-glucosidase and β-glucuronidase inhibiton and ...
Yahia Mabkhot +3 more
openaire +2 more sources
New bis-heterocyclic structures: Synthesis, characterization and biological activity
Journal of Chemical Research, 2023 New bis-heterocyclic compounds were synthesized by reacting two moles of isoniazid, cyanoguanidine and 2-aminophenol with one mole of a bis-chalcone. The bis-chalcone was prepared from the reaction between acetophenone and terephthalaldehyde using sodium hydroxide.
Marwan Mohammed Farhan +2 more
openaire +1 more source
Synthesis of some novel 6,6'-(1,4-phenylene)bis(4-phenylpyrimidin-2-ol/-2-amine/2-thiol catalyzed by MgFe2O4 and evaluation of their antimicrobial activities [PDF]
, 2018 Novel bisheterocycles 4-6 have been synthesized by green approach using cheaper, reusable, non toxic magnetically separable MgFe2O4 as nano catalyst. Bis chalcone and binucleophiles were treated on MgFe2O4 heterogenous catalyst in refluxing ethanol to ...
P. P. Singha, S. Bansala
core +2 more sources
Reactions of Some New Thienothiophene Derivatives
Molecules, 2011 Facile and convenient syntheses of bisdimethylthieno[2,3-b]thiophen-2,5-diyl bis(oxazole-2-amine), bis(1H-imidazol-2-amine), bis((3a)-H-indole),[1,2-a]pyrimidine), bis(1H-imidazo[1,2-b][1,2,4]triazole) and bis(9H-benzo[d]imidazo[1,2-a]imidazole ...
Abdullah Saleh Alamary +4 more
doaj +1 more source
Proceedings, 2019 A solvent-free and catalyst-free synthesis of fused bis-heterocycles containing imidazo[1,2-a]pyridine and tetrazolo[1,5-a]quinoline frameworks is reported via a one-pot process.
Sandra C. Ramírez-López +2 more
doaj +1 more source
Allenamides Playing Domino: A Redox-Neutral Photocatalytic Synthesis of Functionalized 2-Aminofurans [PDF]
, 2022 A photoredox catalytic synthesis of functionalized 2-aminofurans is proposed starting from α-halo carbonyl substrates and N-allenamides. The protocol proves to be efficient and sustainable thanks to: i) the use of visible light as green energy source, ii)
Lombardo M. +6 more
core +1 more source
N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents [PDF]
, 2019 International audienceThe synthesis and evaluation of a series of N,N-bis-heterocyclic-methylamines 1 as isoazaerianin analogues are descriebed. It was demonstrated that the replacement of the 3,4,5-trimethoxyphenyl A-ring present in CA-4, isoCA-4 and ...
Alami, Mouad +8 more
core +1 more source
Antioxidants, 2019 The growing interest in the chemistry of unsaturated ring-fused 1,3-heterocycles, in this particular case 1,3-oxazines, arise in part from their versatile pharmacological applications.
Guadalupe Firpo +10 more
doaj +1 more source
Deprotonative metalation of five-membered aromatic heterocycles using mixed lithium-zinc species
, 2007 International audienceDeprotonation of benzoxazole, benzothiazole, benzo[b]thiophene, benzo[b]furan, N-Boc protected indole and pyrrole, and N-phenylpyrazole using an in situ mixture of ZnCl2*TMEDA (0.5 equiv) and lithium 2,2,6,6-tetramethylpiperidide (1.
Chevallier, Floris +6 more
core +3 more sources