A one‐shot Pd(II)‐catalyzed C─H activation strategy enables the rapid conversion of simple linear propiolamides into structurally diverse mono‐, di‐, and tri‐olefin‐bridged MPAEs. This cascade process orchestrates up to six sequential C–H activations in a single operation, providing streamlined access to highly conjugated architectures.
Haiyu Wang +4 more
wiley +1 more source
Elucidating Ligand-Dependent Selectivities in Pd-Catalyzed C-H Activations. [PDF]
Deufel F, Ravi M, van Gemmeren M.
europepmc +1 more source
Fully Reversible Regulation of 8‐17 DNAzyme Activity Using Nucleoside‐Based Diarylethenes
The site‐specific incorporation of nucleosidic diarylethenes into the 8–17 deoxyribozyme (DNAzyme) identified position 2.1 as optimal. Compound dU‐PhtBu enabled efficient light‐dependent control of catalytic activity, while maintaining thermal stability and reversibility.
Jörn Bargstedt +3 more
wiley +1 more source
Bechgaard Salt-Like Polymers and Their Applications in Organic Electronics. [PDF]
Kolodziejczyk B.
europepmc +1 more source
From Data to Dimers: Engineering Acene Derivatives for Photovoltaic Singlet Fission
Excited‐state energies of acene derivatives are predicted using a ChemBERTa‐based regression model and subsequently used to screen candidates for photovoltaic singlet fission using dimer–monomer benchmarked energetic criteria. Promising candidates are predominantly 5‐ and 6‐fused heteroacenes, which offer enhanced stability and higher triplet energies ...
Alexander J. Cross +2 more
wiley +1 more source
Design, synthesis, anticancer activity, and mechanistic investigation of 4,5,6,7-tetrahydrobenzo[<i>b</i>]thiophene carboxamides as CDK-2 inhibitors: <i>in vitro</i> and <i>in silico</i> DFT and molecular docking study. [PDF]
Anwer KE +6 more
europepmc +1 more source
A library of 21 tetrakis(phenothiazinyl)‐substituted silanes with broadly variable substituent decoration, which are fully reversible multistage redox systems with intense tunable emission from deep blue to yellow–green (441–533 nm), was rapidly synthesized by bromine–lithium exchange/borylation–Suzuki coupling of tetrakis(4‐bromophenyl)silane or by ...
Thomas P. M. Merke +4 more
wiley +1 more source
<i>Rhaponticum</i> genus: a systematic review on traditional uses, phytochemical profiles and pharmacological activities. [PDF]
Wurentuya +7 more
europepmc +1 more source
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
Thermal Behavior of 2,2,3,3,5,5,6,6,8,8,9,9,11,11,12,12-Hexadecamethyl-2,3,5,6,8,9,11,12-octasila-1,4,7,10(2,5)-tetrathiophenacyclododecaphane in the Crystalline State. [PDF]
Nakae T, Yamanoi Y.
europepmc +1 more source

