Results 81 to 90 of about 194,628 (260)

Recent Advances in Microalgae‐Based Functional Coatings and Films for Food Packaging Applications: Opportunities and Challenges

Packaging Technology and Science, EarlyView.
Microalgae‐derived bioactive compounds exhibit strong antioxidant and antimicrobial properties and can be incorporated into edible coatings to enhance food quality and shelf life. These materials offer sustainable, biodegradable alternatives to conventional packaging, with promising potential for future scalable food applications.
Madhu Gaidher, Nidhi Bhardwaj, Sachin Sharma, Akanksha Singh, Kanika Dulta, P. K. Chauhan, Pooja Yadav, Hira Iqbal, Helen Onyeaka, Soumya Ghosh   +9 more
wiley   +1 more source

Thioredoxin/Txnip: Redoxisome, As a Redox Switch for the Pathogenesis of Diseases

Frontiers in Immunology, 2014
During the past few decades, it has been widely recognized that reducing-oxidizing (Redox) responses occurring at the intra- and extra-cellular levels are one of most important biological phenomena and dysregulated redox responses are involved in the ...
Eiji eYoshihara, So eMasaki, Yoshiyuki eMatsuo, Zhe eChen, Hai eTian, Hai eTian, Junji eYodoi, Junji eYodoi, Junji eYodoi   +8 more
doaj   +1 more source

Natural product based inhibitors of the thioredoxin–thioredoxin reductase system

Org. Biomol. Chem., 2004
Spiroketal naphthodecalins are readily assembled by Barton's base mediated Ullmann binaphthyl ether coupling, Dakin reactions and hypervalent iodine spirocyclization. The core structures can be further diversified by enone addition and Stille coupling reactions.
Wipf, Peter, Lynch, Stephen M., Birmingham, Anne, Tamayo Castillo, Giselle, Jiménez, Allan, Campos, Nefertiti, Powis, Garth   +6 more
openaire   +4 more sources

Peptide‐based responsive molecular fluorescent probes for precision oncology

Responsive Materials, EarlyView.
Peptide‐based responsive fluorescent probes have emerged as adaptive functional materials for precision tumor theranostics, combining tumor‐selective recognition, programmable stimulus responsiveness, and modular tunability. They enable high‐contrast imaging, intraoperative guidance, real‐time monitoring, and multimodal applications, while next ...
Xing Wang, Wen Liu, Jiahao Zhang, Wanqi Wang, Zhicheng Jin, Yuqi Tang, Quan Li   +6 more
wiley   +1 more source

Impact of sleep insufficiency and recovery on cancer development

Sleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source

Glutaredoxins and thioredoxins in plants

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2008
During the 70s and 80s two plant thioredoxin systems were identified. The chloroplastic system is composed of a ferredoxin-dependent thioredoxin, with two thioredoxin types (m and f) regulating the activity of enzymes implicated in photosynthetic carbon assimilation. In the cytosol of heterotrophic tissues, an NADP dependent thioredoxin reductase and a
Meyer, Yves, Siala, Wafi, Bashandy, Talaat, Riondet, Christophe, Vignols, Florence, Reichheld, Jean Philippe   +5 more
openaire   +2 more sources

Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou, Christoforos K. Travlos, Lucas Lage Marinho, Thomas A. Mavrakanas, João Pedro Ferreira, Abhinav Sharma   +5 more
wiley   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

The FEBS Journal, EarlyView.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril, Matthieu Le Gallo, Elodie Lafont   +2 more
wiley   +1 more source