Results 91 to 100 of about 7,819 (191)

Repurposing thioridazine as a novel treatment for melanoma brain metastasis

Background A substantial proportion of patients with melanoma brain metastases (MBM), especially those symptomatic at therapy start, continue to respond poorly to currently available systemic therapies, including immune checkpoint ...
Tobias Wikerholmen, Emma Rigg, Erlend Moen Taule, Jian Wang, Hege Avsnes Dale, Terje Sundstrøm, Frits Thorsen, Katharina Sarnow   +7 more
core   +1 more source

Global transcriptional response of methicillin-resistant Staphylococcus aureus to thioridazine

, 2011
Few drugs are available against methicillin-resistant S. aureus (MRSA), and decreased susceptibility among staphylococci to newly introduced agents such as linezolid, daptomycin, and tigecycline has been observed [1-3].
Jacobsen, Kirstine, Bonde, Mette, Klitgaard, Janne Kudsk; id_orcid, Kallipolitis, Birgitte H.; id_orcid, Kolmos, Hans Jørn   +4 more
core   +1 more source

Repurposing Antipsychotic Agents in Oncology: Mechanistic Rationale, Emerging Evidence, and Therapeutic Potential. [PDF]

Cancers (Basel)
Qu A, Gray K, Fattani S, Ansari S, Hamed H, El-Halawany MS, Mondal D, Makhlouf MM, Abd Elmageed ZY.   +8 more
europepmc   +1 more source

Pharmacological Modulators of TCTP: Opportunities and Challenges for Drug Repurposing. [PDF]

Int J Mol Sci
Andrzejczyk W, Porębska K, Balasubramaniyam T, Synowiec A, Kloc M, Stączek P, Kubiak JZ.   +6 more
europepmc   +1 more source

Exploring the Role of Metabolites in Torsadogenic Risk Assessment: A Text-Mining Approach. [PDF]

Turk J Pharm Sci
Bilgin E, Tuğcu G, Aydın A.
europepmc   +1 more source

Assessment of psychotropic medicines utilization patterns for the treatment of mental and neurological disorders in Public Hospitals of Hadiya Zone, Southern Ethiopia: A record-based study. [PDF]

PLOS Ment Health
Tirore MG, Fenta TG, Teshale AA.
europepmc   +1 more source

Exosomal gene-based predictive model and therapeutic target identification for Alzheimer's disease: A bioinformatics analysis. [PDF]

PLoS One
Ma L, Wang D, Li Z, Ye G, Chen M.
europepmc   +1 more source

Phenothiazine Derivatives and Their Impact on the Apoptosis Processes: A Review. [PDF]

J Appl Toxicol
Otręba M, Marek Ł, Paduszyński P, Stojko J, Rzepecka-Stojko A.   +4 more
europepmc   +1 more source

Identification and Characterization of Static Craniofacial Defects in Pre-Metamorphic <i>Xenopus laevis</i> Tadpoles. [PDF]

J Dev Biol
Jones E, Fonticella JM, McLaughlin KA.
europepmc   +1 more source

First-generation antipsychotic shortages in the United States: Utilization and switching patterns. [PDF]

Explor Res Clin Soc Pharm
Tabah A, Swamy N, English C.
europepmc   +1 more source