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Concentrations of thioridazine and thioridazine metabolites in erythrocytes
Psychopharmacology, 1986The concentrations of thioridazine and its main metabolites in erythrocytes from 61 thioridazine-treated patients were determined by gas-liquid chromatography. The mean and range of the erythrocyte concentrations, expressed as percentage of the corresponding plasma concentrations, were: thioridazine, 5.1% (2.0-10.6); side-chain sulfoxide, 5.6% (1.6-10 ...
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To the Editor.— At Norristown (Pa) State Hospital, we have had considerable experience in the use of thioridazine (Mellaril), primarily with schizophrenics, but also with patients with nonpsychotic severe anxiety reactions. It is well known that thioridazine, because of its adrenolytic activity, inhibits or prevents ejaculation in some patients ...
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