Results 81 to 90 of about 7,819 (191)

The Effect of Fluphenazine and Thioridazine on Toxoplasma gondii In Vivo

Iranian Journal of Parasitology, 2016
Background: Toxoplasma gondii is the most common parasite causing latent cerebral infections in human. It has been shown that some anti-psychotic drugs are able to inhibit the proliferation of the parasite in in vitro study.
Mehrzad SARAEI, Yosef GHADERI, Tahereh MOSAVI, Mojtaba SHAHNAZI, Marjan NASSIRI-ASL, Hassan JAHANIHASHEMI   +5 more
doaj  

Exploring the potential of Triton X-100–assisted thioridazine–rose Bengal adduct as an optical chemosensing probe for detection of thioridazine drug residues in water

Sensing and Bio-Sensing Research
Precise quantification of thioridazine (TDZ) drug residues in water samples is essential due to its widespread use. Thus, this study reports low-cost optical chemosensing probe based on Triton X-100 assisted thioridazine (TDZ) -rose Bengal (RB) associate
T.N. Abduljabbar, R.Z. Alhasawi, M.S. El-Shahawi   +2 more
doaj   +1 more source

Chromatographic separation of thioridazine sulphoxide and N-oxide diastereoisomers: identification as metabolites in the rat

, 1986
(±)-Thioridazine and (±)-desmethylthioridazine have been oxidized to produce a number of chiral sulphoxide and amine oxide compounds. Diastereoisomeric isomers were separated by thin-layer and high performance liquid chromatography.
Robin Whelpton, Geraldine M Watkins, Stephen H Curry, Dennis G Buckley   +3 more
core   +1 more source

Thioridazine affects transcription of genes involved in cell wall biosynthesis in methicillin-resistant Staphylococcus aureus

, 2011
The antipsychotic drug thioridazine is a candidate drug for an alternative treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) in combination with the β-lactam antibiotic oxacillin.
Dorte H. Højland, Birgitte H. Kallipolitis, Janne K. Klitgaard, Bonde, Mette, Klitgaard, Janne Kudsk; id_orcid, Kallipolitis, Birgitte H.; id_orcid, Hans Jørn Kolmos, Mette Bonde, Højland, Dorte Heidi, Kolmos, Hans Jørn   +9 more
core   +1 more source

Effect of thioridazine on endocytic vesicles/phagosomes acidification.

, 2016
Confocal microscopy of human monocyte-derived macrophages infected with M. bovis BCG-GFP and stained with LysoTracker Red. A) to C): non-treated cells and (D) brightfield for non-treated cells; E) to G): cells treated with 2.5 μg/ml thioridazine (TZ ...
Diana Machado (327130), Isabel Portugal (327133), David Pires (2327011), Leonard Amaral (69130), Elsa Anes (248979), Isabel Couto (69126), Miguel Viveiros (69123), João Perdigão (327131), Marta Martins (69128)   +8 more
core   +1 more source

Dextromethorphan and mephenytoin phenotyping of patients treated with thioridazine or amitriptyline.

, 1992
The metabolism of most tricyclic antidepressants and some phenothiazine neuroleptics is under the genetic control of hepatic cytochrome P-450IID6, which also regulates the metabolism of dextromethorphan.
Jonzier-Perey, M., Baettig, D., Baumann, P., Koeb, L., Monney, C., Meyer, J.W., Amey, M., Bryois, C., Woggon, B.   +8 more
core   +1 more source

Ca2+ transport by the synaptosomal plasma membrane Ca2+-ATPase and the effect of thioridazine

, 2004
Thioridazine inhibits the activity of the synaptic plasma membrane Ca2+-ATPase from pig brain and slightly decreases the rate of Ca2+ accumulation by synaptic plasma membrane vesicles in the absence of phosphate.
Palacios, J., Mata, A.M., Lee, A.G., Sepulveda, M.R.   +3 more
core   +1 more source

Prognostic Factors and Treatment Outcomes in Pediatric Balamuthia Amoebic Encephalitis: A Case Report and Literature Review

Infectious Microbes & Diseases
Balamuthia amoebic encephalitis (BAE) is a rare and often fatal central nervous system infection caused by the free-living protozoon Balamuthia mandrillaris. Identifying the prognostic factors that affect the survival of pediatric patients is crucial for
Juan-Juan Liu, Yong-Ping Xie, Lei Wang, Lv-Chang Zhu, Yi Shi, Wu-Jie Shi, Ao-Le Li, Wang Hua, Zhi-Peng Shen, Da-Qing Ma, Li-Su Huang   +10 more
doaj   +1 more source

<b> Photo-oxidative damage to isolated rat liver mitochondria induced by phenothiazines </b>

Revista de Ciências Farmacêuticas Básica e Aplicada, 2009
<p class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: normal; text-align: justify; mso-layout-grid-align: none;"> Photosensitization is a well-known side-effect of phenothiazines that could involve photochemically promoted oxidative damage ...
T. RODRIGUES, P. A.F. FARIA, F. S. PESSOTO, C. G. SANTOS, I. L. NANTES   +4 more
doaj  

Akute Intoxikationen mit Thioridazin = acute poisoning with thioridazine

, 1996
OBJECTIVE: As previous single case reports have indicated that acute poisoning with thioridazine can be potentially dangerous, an investigation was undertaken to find out whether the risk of severe poisoning in adults and children can be judged from the ...
Wyss, P. A., Schürch, F., Meier, P. J.
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