Results 111 to 120 of about 2,711 (217)

GPR35 inhibits TRPA1-mediated colonic afferent hypersensitivity through suppression of Substance P release

, 2023
Gupta RA, Higham JP, Urriola-Muñoz P, Barker KH, Paine L, Ghooraroo J, Hockley JR, Rahman T, Smith ESJ, Brown AJ, Suzuki R, Bulmer DC.   +11 more
europepmc   +1 more source

Sustainable Joullié-Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors. [PDF]

J Med Chem
Alfano AI, Pelliccia S, Barone S, Cutarella L, Cancade SMI, Baia V, Cassese E, Russomanno P, Messano N, Frank D, Weizel L, Rotter MJ, Brunst S, Wichelhaus TA, Proschak E, Tedesco D, Mori M, Docquier JD, Summa V, Brindisi M.   +19 more
europepmc   +1 more source

Neprilysin 2 catalyses the degradation of natriuretic peptides despite sacubitrilat Inhibition. [PDF]

Sci Rep
Selezneva EM, Feygina EE, Ageeva LV, Rozov FN, Kopylova IV, Altshuler EP, Semenov AG.   +6 more
europepmc   +1 more source

Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward. [PDF]

Cell Rep, 2022
Dai KZ, Choi IB, Levitt R, Blegen MB, Kaplan AR, Matsui A, Shin JH, Bocarsly ME, Simpson EH, Kellendonk C, Alvarez VA, Dobbs LK.   +11 more
europepmc   +1 more source

Somatostatin-evoked Aβ catabolism in the brain: Mechanistic involvement of α-endosulfine-K_ATP channel pathway. [PDF]

Mol Psychiatry, 2022
Watamura N, Kakiya N, Nilsson P, Tsubuki S, Kamano N, Takahashi M, Hashimoto S, Sasaguri H, Saito T, Saido TC.   +9 more
europepmc   +1 more source

Effect of S-Thiorphan(BP102), on Myocardial Hypertrophy of The Ral Aortic Valve Insufficiency Model

, 1995
Masahiko Kimura, Kazuhiro Kosupe, Masahiko Nishimoio, Kazuo Umemura, Kyoichi Ohashi, Milsuyoshi Nakashima   +5 more
openalex   +1 more source

Comprehensive review on neprilysin (NEP) inhibitors: design, structure-activity relationships, and clinical applications. [PDF]

Front Pharmacol
Zhang X, Hu C, Tian E, Shen Y, Liu W, Li J.   +5 more
europepmc   +1 more source

Drug similarity and structure-based screening of medicinal compounds to target macrodomain-I from SARS-CoV-2 to rescue the host immune system: a molecular dynamics study. [PDF]

J Biomol Struct Dyn, 2022
Babar Z, Khan M, Zahra M, Anwar M, Noor K, Hashmi HF, Suleman M, Waseem M, Shah A, Ali S, Ali SS.   +10 more
europepmc   +1 more source

Complex-Forming Properties of the Anti-Inflammatory Sialorphin Derivative Palmitic Acid-Lysine-Lysine-Glutamine-Histidine-Asparagine-Proline-Arginine with Cu(II) Ions in an Aqueous Solution. [PDF]

Molecules, 2023
Pająk M, Kamysz E, Sikora K, Fichna J, Woźniczka M.   +4 more
europepmc   +1 more source

An integrated biophysical approach to discovering mechanisms of NDM-1 inhibition for several thiol-containing drugs. [PDF]

J Biol Inorg Chem, 2020
Fullington S, Cheng Z, Thomas C, Miller C, Yang K, Ju LC, Bergstrom A, Shurina BA, Bretz SL, Page RC, Tierney DL, Crowder MW.   +11 more
europepmc   +1 more source