Results 131 to 140 of about 2,776 (198)

Insulin restores renal neprilysin (NEP) and attenuates the shedding of urinary NEP and KIM-1 in diabetic Akita mice. [PDF]

Front Pharmacol
Gill RK, Salem ESB, Grobe N, Elased KM.
europepmc   +1 more source

Harder than Metal: Challenging Antimicrobial Resistance with Metallo-β-lactamase Inhibitors. [PDF]

J Med Chem
De Falco A, Alfano AI, Cutarella L, Mori M, Brindisi M.   +4 more
europepmc   +1 more source

Endothelin in man: studies in pharmacology, physiology and pathophysiology [PDF]

, 1999
Ferro, Charles Joseph
core  

A comprehensive review of the literature on CD10: its function, clinical application, and prospects. [PDF]

Front Pharmacol
Wang S, Xiao Y, An X, Luo L, Gong K, Yu D.   +5 more
europepmc   +1 more source

Bradykinin's carbamylation as a mechanistic link to impaired wound healing in patients with kidney dysfunction. [PDF]

BMC Biol
Kaminska M, Kałucka U, Babickova J, Benedyk-Machaczka M, Skandalou E, Grant MM, Marti HP, Mydel P.   +7 more
europepmc   +1 more source

Sacubitril/Valsartan attenuates progression of diabetic cardiomyopathy through immunomodulation properties: an opportunity to prevent progressive disease. [PDF]

Cardiovasc Diabetol
Karuna N, Kerrigan L, Edgar K, Ledwidge M, McDonald K, Grieve DJ, Watson CJ.   +6 more
europepmc   +1 more source

Gut-specific Neprilysin Deletion Protects Against Fat-induced Insulin Secretory Dysfunction in Male Mice.

Endocrinology
Esser N, Mongovin SM, Barrow BM, Zraika S.   +3 more
europepmc   +1 more source

Polarization Controlled Assembly of Ultrathin Thiorphan Nanostructures on ZnO Surface Facets

Langmuir, 2023
Despite the importance of thiorphan as a small molecule with vital biological roles, its interactions with zinc oxide (ZnO) nanomaterials that are prospective in drug delivery and theranostic applications have not yet been sufficiently explored.
Egor Ukraintsev, Hadi Hematian, Bohuslav Rezek   +2 more
openaire   +3 more sources

The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

Nature, 1980
There is both theoretical and therapeutic interest in establishing whether the signals conveyed by the enkephalins are turned off under the action of a specific peptidase which might, in this case, represent a target for a new class of psychoactive agents.
B P, Roques, M C, Fournié-Zaluski, E, Soroca, J M, Lecomte, B, Malfroy, C, Llorens, J C, Schwartz   +6 more
openaire   +3 more sources

Thiorphan potentiation of stress-induced analgesia in the mouse

Life Sciences, 1982
Experiments were done to examine the analgesic effect of thiorphan alone or in combination with stress in mice. Analgesia was assessed by measuring jump latencies from a 55 degrees C hot plate. Thiorphan exhibited weak analgesic properties evidenced by significant increases in jump latencies only after 300 mg/kg i.p. Additional experiments were done to
R, Greenberg, E H, O'Keefe
openaire   +3 more sources