Results 121 to 130 of about 5,312,533 (301)

Real‐World Effectiveness and Safety of Secukinumab in Giant Cell Arteritis: An Italian Multicenter Cohort Study

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in patients with giant cell arteritis (GCA). Methods This multicenter retrospective study included patients with GCA who received secukinumab at 14 Italian centers with at least six months of follow‐up.
Luca Iorio, Federica Davanzo, Caterina Ricordi, Milena Bond, Ruggiero Mascolo, Jacopo Mora, Alessandro Tomelleri, Angelo Fassio, Francesca Cuzzocrea, Sara Monti, Edoardo Conticini, Fabiola Atzeni, Paolo Delvino, Carlotta Nannini, Augusta Ortolan, Francesco Pollastri, Ester Vivaldelli, Chiara Marvisi, Paola Toniati, Antonio Brucato, Alessandra Milanesi, Francesca Regola, Enrico Tombetti, Lorenzo Dagna, Roberta Ramonda, Christian Dejaco, Luca Quartuccio, Carlo Salvarani, Roberto Padoan   +28 more
wiley   +1 more source

The causal relationship between gut microbiota and tinnitus based on Mendelian randomization

Guangxi Yike Daxue xuebao
Objective To explore the causal relationship between gut microbiota and tinnitus based on Mendelian randomization (MR) research method. Methods Data on the gut microbiota in individuals from the genome wide association study (GWAS) (n=18, 340) using the ...
LIANG Yinfei, ZHOU Jingshi, ZHANG Shuqi, LI Lingwei, GU Jing, WEN Zhiyang, WU Dongxue, LI Zhicheng, ZENG Xiangli   +8 more
doaj   +1 more source

Rheumatoid Arthritis, Frailty, and Outcomes of Surgical Hospitalizations: A National Population‐Based Analysis

Arthritis Care &Research, EarlyView.
Objective Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective noncardiac surgery. Methods We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including adults
Ali Yazdanyar, Joshua Baker, Katherine D. Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

ALYREF-mediated RNA 5-methylcytosine modification promotes laryngeal cancer progression via stabilizing DDX11 mRNA

Scientific Reports
Laryngeal cancer (LC) is one of the malignant tumors affecting the head and neck region. 5-methylcytosine (m5C) is a common RNA modification that contributes to the carcinogenesis process.
Shanyan Bian, Rui Li, Yingwei Guo, Yingtao Wu, Jianqi Zhao, Zhiyuan Wang, Jiancong Huang   +6 more
doaj   +1 more source

Triple semicircular canal occlusion with endolymphatic sac decompression for intractable Meniere’s disease

Frontiers in Neurology
BackgroundMeniere’s disease (MD) is characterized by idiopathic endolymphatic hydrops (ELH). Frequent vertigo attacks is the most disabling symptom of MD.ObjectiveThis study evaluated the efficacy of triple semicircular canal occlusion combined with ...
Jiawang Tian, Gendi Yin, Qian Zhang, Shuqi Zhang, Xiangli Zeng, Yongqi Li   +5 more
doaj   +1 more source

Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns

Arthritis Care &Research, Accepted Article.
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen, Yasuo Nagafuchi, Kristina Lend, Seyam Alemyar, Herman Kasper Glas, Gerdur Gröndal, Bjorn Gudbjornsson, Espen A. Haavardsholm, Kim Hørslev Petersen, Jon Lampa, Merete Lund Hetland, Dan Nordström, Mike Nurmohamed, Mikkel Østergaard, Anna Rudin, Marte Schrumpf Heiberg, Tuulikki Sokka‐Isler, Till Uhlig, Josien Veris‐van Dieren, Ronald van Vollenhoven, Tom Huizinga, Marcel JT Reinders, Sytske Anne Bergstra, Erik van den Akker, Rachel Knevel   +24 more
wiley   +1 more source

Opportunity and influence: the third sector and the 2010 general election

, 2010
This paper explores how the different voices and interests of the third sector, political parties and media have shaped and reflected the policy agenda over the course of the 2010 general election campaign and into the early post-election period.
Parry, Jane, Pete, Alcock, Kendall, Jeremy   +2 more
core   +1 more source

Development of Patient‐Reported Outcome Measures for Early Systemic Sclerosis Across Disease Subtypes

Arthritis Care &Research, Accepted Article.
Objective Existing patient‐reported outcome (PRO) measures for systemic sclerosis (SSc) have important limitations, including inadequate coverage of early disease and limited inclusion of diffuse cutaneous (dcSSc) and limited cutaneous (lcSSc) subtypes.
George J. Greene, Chelsea Rose Perschon, Emilie Jaeger, Alain Lescoat, David Cella, Dinesh Khanna   +5 more
wiley   +1 more source

Blood Eosinophil Count and Lund–Mackay Ethmoid Score as Predictors of Recurrence After Endoscopic Sinus Surgery in CRSwNP

Laryngoscope Investigative Otolaryngology
Objectives To evaluate the incremental prognostic value of blood eosinophil count (BEC) and Lund–Mackay (LM) ethmoid score beyond age and asthma for recurrence after endoscopic sinus surgery (ESS) in adults with chronic rhinosinusitis with nasal polyps ...
Zikang Xiao, Ru Gao, Yu Chen, Tiansheng Wang   +3 more
doaj   +1 more source

Artificial Intelligence‐Driven Extraction of Patient‐Reported Pain Outcomes in Osteoarthritis Using Large Language Models

Arthritis Care &Research, Accepted Article.
Objective Patient‐reported outcome measures (PROMs) are central to assessing symptom burden and treatment response in Osteoarthritis (OA) but are often embedded in unstructured clinical notes. We evaluated whether prompt‐engineered large language models (LLMs) could accurately extract or infer pain scores on a 0‐10 scale from routine OA clinical ...
Jainesh Doshi, Stephen Batter, Yiyuan Wu, William Salerno, Alice Santilli, Sandhya Kannayiram, Susan Goodman, Bella Mehta   +7 more
wiley   +1 more source