Results 51 to 60 of about 213,846 (255)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Self-reported Difficulties in Learning English as a Second Language for Third-age Students in Poland

open access: yesTheory and Practice of Second Language Acquisition, 2019
The problem of teaching English to third-age students is among the issues in ELT which have gained increasing attention and interest in recent years. The aim of this paper is to identify difficulties in learning English as a foreign language reported by
Łukasz Matusz, Anna Maria Rakowska
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Memory systems modulate crosslinguistic influence on third language morphosyntactic acquisition.

open access: yesPLoS ONE
Previous studies on crosslinguistic influence (CLI) on third language (L3) morphosyntactic acquisition have provided support for competing theories about the source(s) of CLI.
Emily Shimeng Xu   +3 more
doaj   +1 more source

Bilingualism and Access to the Spanish Language by Russian-Romanian Bilinguals

open access: yesDarnioji daugiakalbystė, 2017
Bilingualism is a complex process involving a variety of characteristics, among which we can distinguish a particular system of a language, as well as the ability to use it in communication. Apart from the mere fact of acquiring the knowledge of a second
Antonchuk Daniela
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

The Effect of the Second Language on Metalinguistic Awareness in Third Language Vocabulary Learning

open access: yesRomanian Journal of English Studies, 2021
This study aims at investigating the effect of second language in third language learning. It focuses on metalinguistic awareness, which reflects the extent to which learners can use their background languages in the process of third and additional ...
Sadouki Fatiha
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Third Languages Acquisition (TLA): Educational Multilingualism at Early Ages

open access: yesLanguages
In an increasingly globalized world, learning foreign languages (FLs) is essential, particularly in education. Multilingualism is critical due to the multicultural and interconnected nature of societies, yet early third language acquisition (TLA) is not ...
M.ª Dolores Asensio Ferreiro
doaj   +1 more source

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