Results 61 to 70 of about 1,946,102 (269)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Oscillation criteria for third-order nonlinear differential equations with functional arguments

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we consider the third-order nonlinear differential equations with functional arguments. By using the Riccati inequality, we find conditions for all solutions to be oscillatory.
Yutaka Shoukaku
doaj  

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Oscillation of solutions for third order functional dynamic equations

open access: yesElectronic Journal of Differential Equations, 2010
In this article we study the oscillation of solutions to the third order nonlinear functional dynamic equation $$ L_{3}(x(t))+sum_{i=0}^{n}p_i(t)Psi_k{alpha_ki}(x(h_i(t)))=0, $$ on an arbitrary time scale $mathbb{T}$.
Elmetwally M. Elabbasy, Taher S. Hassan
doaj  

Third order optical nonlinearity of graphene

open access: yesNew Journal of Physics, 2014
We perform a perturbative calculation of the third order optical conductivities of doped graphene, using approximations valid around the Dirac points and neglecting effects due to scattering and electron–electron interactions.
J L Cheng, N Vermeulen, J E Sipe
doaj   +1 more source

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