Results 81 to 90 of about 2,006,273 (266)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Oscillation criteria for third-order nonlinear differential equations with functional arguments
Electronic Journal of Differential Equations, 2013 In this article, we consider the third-order nonlinear differential equations with functional arguments. By using the Riccati inequality, we find conditions for all solutions to be oscillatory.
Yutaka Shoukaku
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Oscillation of solutions for third order functional dynamic equations
Electronic Journal of Differential Equations, 2010 In this article we study the oscillation of solutions to the third order nonlinear functional dynamic equation $$ L_{3}(x(t))+sum_{i=0}^{n}p_i(t)Psi_k{alpha_ki}(x(h_i(t)))=0, $$ on an arbitrary time scale $mathbb{T}$.
Elmetwally M. Elabbasy, Taher S. Hassan
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Journal of Taibah University for Science, 2019 The authors present some new oscillation criteria for third order nonlinear differential equations with a nonlinear nonpositive neutral term. The results obtained are new and improve known oscillation criteria appearing in the literature even for ...
Said R. Grace +2 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Subharmonic oscillation in third order non-linear systems
Vietnam Journal of Mechanics, 1979 In this paper the subharmonic oscillation with frequency n times smaller than that of exciting force is considered. The first paragraph is devoted to the formulation of problem.
Nguyen Van Dao
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Existence of solutions to a third-order multi-point problem on time scales
Electronic Journal of Differential Equations, 2007 We are concerned with the existence and form of solutions to nonlinear third-order three-point and multi-point boundary-value problems on general time scales.
Joan Hoffacker, Douglas R. Anderson
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