Results 71 to 80 of about 11,827,018 (250)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Positive solutions of third order damped nonlinear differential equations [PDF]
, 2011 summary:We study solutions tending to nonzero constants for the third order differential equation with the damping term \[ (a_{1}(t)(a_{2}(t)x'(t))')'+q(t)x'(t)+r(t)f(x(\varphi (t)))=0 \] in the case when the corresponding second order differential ...
Cecchi, Mariella +3 more
core +1 more source
Optimisation of a Third Order System
Measurement + Control, 1971 A general algebraic method of optimising a third order system is presented. The method consists of extending Pontryagin's Maximum Principle to the infinite interval case and reducing the characteristic two point boundary value problem to that of the ...
L. H. Lees
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Offender engagement with third sector organisations: a national prison-based survey [PDF]
, 2011 This paper is the second in a series that investigates the involvement of the third sector in the resettlement of prisoners. Working paper 57 found that nearly 20,000 third sector organisations reported engagement in work with offenders through seven ...
Mills, Alice +2 more
core +1 more source
Analýza sociálnej štruktúry stredovekej spoločnosti [PDF]
Historická sociologie, 2013 This study concentrates on the analysis of social structure of medieval society and accordingly on the acquisition of knowledge (1) about their orderliness, (2) inner processes (3) and least partially their influence on the process of formation of West ...
Margita Minichová
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Third-order Theory and Aspheric Spectacle Lens Design
, 1984 Third-order equations are developed giving sagittal and tangential power errors corresponding to the eye rotating to look through the periphery of a spectacle lens. The equations are applicable for conicoid aspherical surfaces.
David A. Atchison, Atchison, David A.
core +1 more source
MathematicsThis paper focuses on the oscillatory properties of the third-order semi-canonical nonlinear delay differential equation. By using the new canonical transform method, we transformed the studied equation into a canonical-type equation, which simplified ...
Ekambaram Chandrasekaran +3 more
doaj +1 more source