Results 161 to 170 of about 671,106 (305)

Education Research: Feasibility and Impact of Academic Half-Day at a Large Academic Neurology Residency Program. [PDF]

open access: yesNeurol Educ
Greenberg JH   +10 more
europepmc   +1 more source

Patient‐reported outcome measures of percutaneous nephrostomy vs JJ stent in obstructive urolithiasis: results of the STent Or NEphrostomy (STONE) randomised controlled trial

open access: yesBJU International, EarlyView.
Objective To compare the effects of percutaneous nephrostomy (PCN) and JJ ureteric stent (JJ) for urinary tract decompression in patients with obstructive urolithiasis on health‐related quality of life (HRQoL), pain scores, urinary symptoms, and patient satisfaction.
Hugo W. Schuil   +25 more
wiley   +1 more source

Evidence of emerging transcriptome mediators of Alzheimer's disease in canine cognitive dysfunction

open access: yesBrain Pathology, EarlyView.
Canine cognitive dysfunction (CCD) may be a promising model of Alzheimer's disease (AD). To assess AD‐related molecular signatures in CCD, we generated transcriptome data on dog cortex and plasma extracellular vesicles (EVs). CCD‐related transcriptome changes were similar to those in aging/AD humans and were detectable in EVs from the same animals ...
Shelby C. Osburn   +7 more
wiley   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof   +8 more
wiley   +1 more source

Impact of endometrioma on iron levels and oxidative stress in the follicular fluid in women with endometriosis: a cross-sectional study. [PDF]

open access: yesSci Rep
Peter M   +11 more
europepmc   +1 more source

Sex-Specific Differences in Patients with Hypertrophic Cardiomyopathy: A Cohort Study from Vienna. [PDF]

open access: yesJ Pers Med
Mann C   +9 more
europepmc   +1 more source

Patient‐Derived IgG Epitope Mapping of Bet v 1 Reveals Hypoallergenic Peptide Candidates for Safe and Next‐Generation Allergen Immunotherapy

open access: yesClinical &Experimental Allergy, EarlyView.
Mapping IgG epitopes of the major birch allergen Bet v 1 identified patient‐derived, hypoallergenic peptides that did not trigger degranulation. These findings support a novel, safer approach for peptide‐based allergen immunotherapy that leverages naturally induced IgG specificities from allergic individuals. ABSTRACT Background Allergen immunotherapy (
Lara Šošić   +10 more
wiley   +1 more source

Cold‐blooded commerce: Characterizing and predicting trade in Australian squamates

open access: yesConservation Science and Practice, EarlyView.
Despite a national ban on native wildlife exports, Australian reptile species continue to appear in international trade. Using boosted regression trees, we found that large body sizes and taxonomic family, rather than color or patterning, best predicted trade presence. We identified 59 species likely to be targeted in the future, providing key insights
Sebastian Chekunov   +5 more
wiley   +1 more source

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