Results 61 to 70 of about 67,801 (257)

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman   +5 more
wiley   +1 more source

Molecular Palaeontology Prospects From Exceptionally Preserved Eocene Brackish‐Water Bivalve Batissa sitakaraensis (Venerida: Corbiculidae) From Hokkaido, Japan

open access: yesGeological Journal, EarlyView.
This study reports the exceptional preservation of the Eocene freshwater bivalve Batissa sitakaraensis from Hokkaido, Japan. Multimodal analyses reveal that both the aragonitic shell mineralogy and the delicate organic periostracum retain their original structural and chemical characteristics after millions of years.
Taro Yoshimura   +4 more
wiley   +1 more source

Mythologie der Unvernunft

open access: yesCahiers d’Études Germaniques, 2019
Thomas Mann’s Faustus has been blamed to reverse the German nationalist myth of the Faustian character into an anti-nationalist and dark opposite, and continue the irrational interpretation of history.
Stefan Matuschek
doaj   +1 more source

Thomas Mann

open access: yesLetras (Lima), 1929
Thomas Mann, a quien la Academia sueca acaba de discernir el premio Nobel, pertenece, con su hermano Heinrich, al grupo de escritores que en Alemania representa un altísimo ideal europeo de paz y  solidaridad continental. Contra arraigadas exigencias de un exclusivismo tradicional, los dos grandes novelistas trabajan, sobre todo después de la guerra ...
openaire   +2 more sources

Plasma PlGF as a Potential Biomarker in Ramucirumab‐Based Second‐Line Therapy for Advanced Gastroesophageal Adenocarcinoma: Exploratory Biomarker Analysis from the Phase II Part of the RAMIRIS Trial

open access: yesInternational Journal of Cancer, EarlyView.
Antiangiogenic treatment with ramucirumab is a standard second‐line option in advanced gastric and gastroesophageal junction adenocarcinoma. However, reliable biomarkers are currently lacking. This exploratory biomarker analysis of the RAMIRIS trial suggests that elevated baseline and early on‐treatment levels of the pro‐angiogenic placental growth ...
Jurek Hille   +17 more
wiley   +1 more source

A Serum lncRNA Signature Determines Oncogenic YAP Activity in Cancer Patients

open access: yesInternational Journal of Cancer, EarlyView.
Long non‐coding RNAs (lncRNAs) signatures are promising cancer biomarkers, since their dysregulation in tumors is reflected in body fluids. In this study, next‐generation sequencing, bioinformatics, and gene expression data were combined to investigate an lncRNA signature linked specifically to the cancer‐promoting YAP in several cancer types ...
Fabian Rose   +24 more
wiley   +1 more source

A Banalização da Vida em Dr. Fausto ou O Mal segundo Thomas Mann

open access: yesCaminhos, 2008
O texto analisa o significado do mal no romance Doutor Fausto, de Thomas Mann.
Ana Lúcia Modesto
doaj   +1 more source

High‐Throughput Geocoding to Assess Short‐Term Air Pollution in Correlation With Mortality in a French Cancer Patient Cohort

open access: yesInternational Journal of Cancer, EarlyView.
Although chronic air pollution exposure is linked to lung cancer mortality, the short‐term effects of fluctuating air quality on overall cancer mortality remain uncertain. Here, the authors applied geomatics and machine‐learning models to retrospectively examine possible associations between 31‐day pollution exposure and mortality in a French cancer ...
Loice Pokam   +12 more
wiley   +1 more source

Thomas Mann und die beiden totalitären Diskurse des Judentums: Überlegungen zu seinen publizistischen Schriften (1907-1933)

open access: yesRevista de Filología Alemana, 2007
It is obvious that the jew related totalitarisms (zionism and antisemitism) are writing categories in the work of Thomas Mann. A proof of this is the Berliner Colloquium of 2002 with the title “Thomas Mann und das Judentum”. As writing categories it both
Pierre Kodjio Nenguié
doaj  

The Homological Nature of Entropy

open access: yesEntropy, 2015
We propose that entropy is a universal co-homological class in a theory associated to a family of observable quantities and a family of probability distributions.
Pierre Baudot, Daniel Bennequin
doaj   +1 more source

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