Results 71 to 80 of about 67,801 (257)
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to its asymptomatic progression, late‐stage diagnosis, and treatment resistance. Efforts in early detection have centered on identifying imaging features and liquid biopsy biomarkers capable of detecting PDAC and its high‐grade precursors before clinical symptoms ...
Christine Worthington +105 more
wiley +1 more source
ABSTRACT MET is an actionable receptor tyrosine kinase, and MET‐directed antibody–drug conjugates (ADCs) have recently entered clinical practice with FDA approval in non‐small cell lung cancer and are now being evaluated across gastrointestinal malignancies, with patient selection based on MET immunohistochemistry (IHC) 3+ membranous staining at ...
Tillmann Bedau +7 more
wiley +1 more source
Abstract Background Obesity increases the risk of obstetric and neonatal complications, and adherence to lifestyle interventions during pregnancy presents a challenge. Patient and public involvement (PPI) in trials may foster a more patient‐centered approach, potentially improving compliance with intervention and follow up.
Elisabeth Garcia Vilaplana +6 more
wiley +1 more source
Nedostatečnost ve světle měšťanské epochy: Thomas Mann a Hugo von Hofmannsthal // Inadequacy in the light of the bourgeois age — Thomas Mann and Hugo von Hofmannsthal [PDF]
The paper aims to compare two authors of the Fin-de-Siècle from the German-speaking area (Thomas Mann and Hugo von Hofmannsthal) and tries to offer a specific “German” interpretation of contemporary phenomena like dandyism or estheticism.
Štěpán Sirovátka
doaj
The Bridge of Hope: Mediating the Relationship Between Mindfulness and Loneliness
ABSTRACT This cross‐sectional study sought to explore hope as a mediator between mindfulness and loneliness and social connectedness by using a structural equation modeling data analysis approach to analyze the relationships. Among a sample of 676 interpersonal trauma experiencers recruited online from a crowdsourcing platform, hope fully mediated the ...
Daniel Gutierrez +2 more
wiley +1 more source
Abstract Background Vancomycin is first‐line treatment for methicillin‐resistant Staphylococcus aureus (MRSA) infections. However, despite guideline recommendations, there is no evidence that targeting vancomycin trough concentrations of ≥15 mg/L in children confers clinical benefit and is associated with vancomycin‐associated nephrotoxicity (VAN ...
Megan R. Nettleton +11 more
wiley +1 more source
Quantifying user variability in the traditional X‐ray ice‐rafted‐debris counting technique
ABSTRACT The flux of icebergs is most commonly constrained in the palaeo‐record by manually counting gravel clasts in sediment core X‐ray images—a trusted method in Quaternary science and palaeoceanography for nearly 40 years. In this study, we explore the reproducibility (user consistency and between‐user variability) of the traditional clast‐counting
Neil McDonald +3 more
wiley +1 more source
Lotte in Weimar: Thomas Mann, Goethe y el exilio
La presencia de Goethe en Thomas Mann se puede encontrar ya en sus obras tempranas. Sin embargo, a partir de los años 20 Goethe empieza a cobrar un significado diferente para Mann como representante de los valores humanistas de la cultura burguesa, en un
Ana Pérez
doaj
Abstract Purpose The presence of a sinus tract in chronic periprosthetic joint infection (PJI) has traditionally been considered a contraindication to single‐stage total knee arthroplasty (TKA) revision. However, an increasing number of surgeons are now performing single‐stage revisions in this context, despite limited comparative data.
Arthur Barbaret +12 more
wiley +1 more source
Ludwig Fertig: Vor-Leben. Bekenntnis und Erziehung bel Thomas Mann.
Sin ...
Arturo Parada Diéguez
doaj

