Results 81 to 90 of about 62,627 (245)

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

Advanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu   +10 more
wiley   +1 more source

Trauma cardíaco: estudo de necropsias

Revista do Colégio Brasileiro de Cirurgiões
RESUMO OBJETIVO: Pacientes vítimas de trauma cardíaco morrem, na maioria das vezes, antes de receberem atendimento médico. Porém, são poucos os estudos epidemiológicos deste tipo de lesão descrevendo a porcentagem de pacientes que chegam a ser tratados ...
Gustavo Pereira Fraga, Luiz Rogério Heinzl, Bárbara Sugui Longhi, Daniel Carlos da Silva, Francisco Américo Fernandes Neto, Mario Mantovani   +5 more
doaj   +1 more source

Outcomes of patients with blunt chest trauma encountered at emergency department and possible risk factors affecting mortality

Journal of Medical Sciences, 2017
Background: Blunt chest trauma is associated with a high risk of mortality. Respiratory complications may necessitate prolonged ventilation and result in death.
Yuan-Ming Tsai, Kuan-Hsun Lin, Tsai-Wang Huang, Chun-Ying Chen, Zhi-Jie Hong, Sheng-Der Hsu   +5 more
doaj   +1 more source

Management of retrograde intraoperative Type A aortic dissection from descending thoracic aortic injury [PDF]

, 2017
Whitney Hornsby, William Weir, Minhaj S. Khaja, Bo Yang   +3 more
openalex   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

Profile of thoracic trauma victims submitted to chest drainage

Revista do Colégio Brasileiro de Cirurgiões
Objective: to describe and compare the variables involved in trauma victims undergoing thoracic drainage. Methods: we conducted a retrospective, analytical, descriptive, cross-sectional study, with medical records of patients attended at the Trauma ...
CESAR AUGUSTO BROSKA JÚNIOR, ADRIANE BARBOSA BOTELHO, ANDRÉ DE CASTRO LINHARES, MARIANA SANTOS DE-OLIVERIA, GABRIELA VERONESE, CARLOS ROBERTO NAUFEL JÚNIOR, LISLAINE CRUZ BATISTA, MARIA ANGÉLICA KURPEL DIOGO   +7 more
doaj   +1 more source

Cervical Spine Injury Without Neurologic Deficit vs Thoracic or Lumbar Spine Injury: Does Location Matter With Regard to Complications? [PDF]

, 2016
Krishna Akella, Akella Chendrasekhar
openalex   +1 more source

Traumatic Brain Injury Associated with Blunt Thoracic Aorta in A 2-Year-Old Child

, 2021
João Brito, Claudio Roberto Assumpção, Gerez Fernandes Martins, Eulalia Pffeifer, Antonio de Padua Jazbik, Lucas Moura B. Maciel, Luisa de Campos Guimaraes, Ernesto Koeler Chaves   +7 more
openalex   +1 more source

Acromioclavicular and sternoclavicular joint dislocations indicate severe concomitant thoracic and upper extremity injuries in severely injured patients [PDF]

, 2020
Mustafa Bakır, Rolf Lefering, Lyubomir Haralambiev, Simon Kim, Axel Ekkernkamp, Denis Gümbel, Stefan Schulz-Drost   +6 more
openalex   +1 more source