Results 131 to 140 of about 90,511 (304)

USP54 Promotes Ferroptosis in Non‐Small Cell Lung Cancer by Mediating FOXA2 Deubiquitination and Enhancing ACSL4 Transcription

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Non‐small cell lung cancer (NSCLC) is the most common type of lung cancer, with a 5‐year survival rate of less than 20% and a high risk of recurrence despite advances in treatment. This study aimed to identify new therapeutic targets to increase the effectiveness of NSCLC treatments.
Rui‐Shi Wei   +5 more
wiley   +1 more source

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best   +17 more
wiley   +1 more source

Weighted Diffeomorphic Density Matching with Applications to Thoracic Image Registration

open access: yes, 2015
In this article we study the problem of thoracic image registration, in particular the estimation of complex anatomical deformations associated with the breathing cycle.
Bauer, Martin   +3 more
core  

Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation

open access: yesThe Laryngoscope, EarlyView.
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal   +3 more
wiley   +1 more source

Head and Neck Metastases From Infraclavicular Primary Tumors: Analysis of 136 Cases

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective Distant metastases in the head and neck region are rare, often posing challenges for ENT specialists and being of crucial importance in the management of infraclavicular primary tumors. Methods The case series presented here aims to outline the relevant aetiologies and clinical presentation in the head and neck region.
Achim M. Franzen   +3 more
wiley   +1 more source

Evaluating Sleep Apnea: In‐Lab Versus at‐Home Recording Time and the Impact of Positional Disease

open access: yesThe Laryngoscope, EarlyView.
We evaluated the minimum recording time needed for in‐lab polysomnography (PSG1) and home sleep apnea test Type 3 portable monitoring (HSAT) to accurately reflect the full‐night apnea–hypopnea index (AHI) in patients with suspected obstructive sleep apnea (OSA).
Raquel Chartuni Pereira Teixeira   +1 more
wiley   +1 more source

Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia   +3 more
wiley   +1 more source

Dose escalation in radical radio(chemo)therapy for cervical and upper thoracic esophageal cancer with 3DCRT/IMRT (ChC&UES): a multicenter retrospective study

open access: yesRadiation Oncology
Background Cervical and upper thoracic esophageal cancer (ESCA) presents treatment challenges due to limited clinical evidence. This multi-center study (ChC&UES) explores radical radio(chemo)therapy efficacy and safety, especially focusing on radiation ...
Xiao-Han Zhao   +16 more
doaj   +1 more source

Deep learning‐based H&E‐derived risk scores in colorectal cancer: associations with tumour morphology, biology, and predicted drug response

open access: yesThe Journal of Pathology, EarlyView.
Abstract Over recent years, several deep learning (DL) models have been presented to predict colorectal cancer (CRC) patient survival directly from haematoxylin and eosin (H&E)‐stained routine whole‐slide images (WSIs). Unlike traditional studies that rely on manually defined histopathological features, weakly supervised DL allows training directly on ...
Nic G Reitsam   +23 more
wiley   +1 more source

What practicing pathologists and oncologists should know about the new computational pathology‐based companion diagnostic tools

open access: yesThe Journal of Pathology, EarlyView.
Abstract The integration of artificial intelligence into pathology is transforming the assessment of histological and immunohistochemical (IHC) slides, offering opportunities to reduce variability and streamline diagnostics. In practical terms, most available tools and research models emulate the diagnostic capabilities of pathologists by detecting ...
Diana Montezuma   +11 more
wiley   +1 more source

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