Results 31 to 40 of about 2,879,945 (110)

Computer-assisted ex vivo, normothermic small bowel perfusion [PDF]

, 2000
Background: In the present study, a technique for computer-assisted, normothermic, oxygenated, ex vivo, recirculating small bowel perfusion was established as a tool to investigate organ pretreatment protocols and ischemia/reperfusion phenomena.
Theodorou, D., Hammer, C., Schildberg, Friedrich Wilhelm, Eder, M., Land, W., Stangl, M. J., Krapp, J.   +6 more
core   +1 more source

Liver transplantation with uncontrolled versus controlled DCD donors using normothermic regional perfusion and ex-situ machine perfusion

, 2023
In Italy, 20 minutes of continuous, flat-line electrocardiogram are required for death declaration, which significantly increases the risks of donation after circulatory death (DCD) LT.
Zanierato M., De Carlis L., De Simone P., Di Salvo M., Lauterio A., Ghinolfi D., Torri F., Farnesi F., Patrono D., Buscemi V., Melandro F., Cerchione R., De Carlis R., Morganti R., Romagnoli R.   +14 more
core   +2 more sources

Maintaining the permanence principle for death during in situ normothermic regional perfusion for donation after circulatory death organ recovery: A United Kingdom and Canadian proposal

American Journal of Transplantation, Volume 20, Issue 8, Page 2017-2025, August 2020., 2020
There is international variability in the determination of death. Death in donation after circulatory death (DCD) can be defined by the permanent cessation of brain circulation. Post‐mortem interventions that restore brain perfusion should be prohibited as they invalidate the diagnosis of death.
Alex Manara, Sam D. Shemie, Stephen Large, Andrew Healey, Andrew Baker, Mitesh Badiwala, Marius Berman, Andrew J. Butler, Prosanto Chaudhury, John Dark, John Forsythe, Darren H. Freed, Dale Gardiner, Dan Harvey, Laura Hornby, Janet MacLean, Simon Messer, Gabriel C. Oniscu, Christy Simpson, Jeanne Teitelbaum, Sylvia Torrance, Lindsay C. Wilson, Christopher J. E. Watson   +22 more
wiley   +1 more source

Datasheet1_Outcomes of liver transplantation with thoracoabdominal normothermic regional perfusion: a matched-controlled initial experience in Spain.zip

, 2023
Thoracoabdominal (TA) normothermic regional perfusion (NRP) should allow the safe recovery of heart and liver grafts simultaneously in the context of controlled donation after circulatory death (cDCD).
Juan Carlos Rodríguez-Sanjuán (17312536), Felipe Alconchel (12258321), Pablo Ramírez (11182971), Gabriel Moreno-González (17312539), Oriana Barrios (17312530), Laura Lladó (2937903), Luis Secanella (17312521), Javier López-Monclús (17312524), Manuel Cecilio Jiménez-Garrido (17312533), Mario Royo-Villanova (15463301), Enrique Toledo-Martínez (17312527)   +10 more
core   +1 more source

Direct procurement of donor heart with normothermic regional perfusion of abdominal organs. [PDF]

, 2019
PURPOSE: To evaluate if direct procurement of heart is possible in combination with normothermic regional perfusion of abdominal organs in donors after circulatory death.

core   +2 more sources

Hypothermic, oxygenated perfusion (HOPE) provides cardioprotection via succinate oxidation prior to normothermic perfusion in a rat model of donation after circulatory death (DCD) [PDF]

, 2021
In donation after circulatory death (DCD), cardiac grafts are subjected to warm ischemia in situ, prior to a brief period of cold, static storage (CSS) at procurement, and ex situ, normothermic, machine perfusion (NMP) for transport and graft evaluation.
Arnold, Maria, Wyss, Rahel K., Segiser, Adrian, Carrel, Thierry P, Carrel, Thierry P., Mueller, Matteo, Longnus, Sarah L; https://orcid.org/, Dutkowski, Philipp, Wyss, Rahel K, Longnus, Sarah L., Méndez Carmona, Natalia   +10 more
core   +1 more source

Donor and recipient risk factors for the development of primary graft dysfunction following lung transplantation

Frontiers in Immunology
Primary Graft Dysfunction (PGD) is a major cause of both short-term and long-term morbidity and mortality following lung transplantation. Various donor, recipient, and technical risk factors have been previously identified as being associated with the ...
J. Asher Jenkins, Ricardo Verdiner, Ashraf Omar, Juan Maria Farina, Renita Wilson, Jonathan D’Cunha, Pedro Augusto Reck Dos Santos   +6 more
doaj   +1 more source

Reference values and physiological characterization of a specific isolated pig kidney perfusion model [PDF]

, 2007
Background: Models of isolated and perfused kidneys are used to study the effects of drugs, hazardous or toxic substances on renal functions. Since physiological and morphological parameters of small laboratory animal kidneys are difficult to compare to ...
Unger Volker, David A Groneberg, Fischer, Axel, Unger, Volker, Groneberg, Jan David Alexander, Groneberg David A, Volker Unger, Grosse-Siestrup Christian, Fehrenberg Claudia, Meissler, Michael, Axel Fischer, Christian Grosse-Siestrup, Fischer Axel, Meissler Michael, Michael Meissler, Grosse-Siestrup, Christian, Fehrenberg, Claudia, Claudia Fehrenberg   +17 more
core   +1 more source

Developing bioethical and regulatory frameworks for research in thoracoabdominal normothermic regional perfusion

JME Practical Bioethics
Heart transplantation remains the gold standard of treatment for end-stage cardiovascular disease, but there is a persistent mismatch between the supply of donor hearts and recipient demand.
Brendan Parent, Justin Tao Wang
doaj   +1 more source

Donation After Circulatory Death in Pediatric Heart Transplantation

Pediatric Transplantation, Volume 30, Issue 5, May 2026.
DCD listing in pediatric HT is associated with a shorter interval between offers, more frequent offers, and similar waitlist survival despite DCD candidates being sicker at listing. There was no difference in 30‐day survival between DCD and DBD recipients. ABSTRACT Purpose Donation after circulatory death (DCD) is an emerging heart transplantation (HT)
Sarah Dudley Grorud, Michael D. Porter, Taufiek Konrad Rajab, R. Jerome Dixon, Michael McCulloch, Firezer Haregu   +5 more
wiley   +1 more source