Results 51 to 60 of about 2,879,945 (110)

DCD heart transplantation with prolonged functional warm and cold ischemic time using controlled hypothermic preservation: A case report

JHLT Open
We describe the case of successful heart transplantation following donation after circulatory death (DCD) with a prolonged functional ischemic time (43 minutes), which was performed using the Paragonix SherpaPak Cardiac Transport System (SCTS).
Vincenzo Tarzia, MD, PhD, Matteo Ponzoni, MD, Marco Gemelli, MD, Nicola Pradegan, MD, Gino Gerosa, MD   +4 more
doaj   +1 more source

Neither Ethical nor Prudent: Why Not to Choose Normothermic Regional Perfusion

Hastings Center Report, Volume 54, Issue 4, Page 14-23, July‐August 2024.
Abstract In transplant medicine, the use of normothermic regional perfusion (NRP) in donation after circulatory determination of death raises ethical difficulties. NRP is objectionable because it restores the donor's circulation, thus invalidating a death declaration based on the permanent cessation of circulation.
Adam Omelianchuk, Alexander Morgan Capron, Lainie Friedman Ross, Arthur R. Derse, James L. Bernat, David Magnus   +5 more
wiley   +1 more source

Extracorporeal normothermic pancreas perfusion [PDF]

, 2016
Pancreas and islet transplantation are important treatment options for insulin dependent diabetes. However, one of the main challenges in pancreas and islet transplantation lies in organ (pancreas) preservation.
Kuan, Kean Guan
core   +1 more source

Considerations for the use of porcine organ donation models in preclinical organ donor intervention research

Animal Models and Experimental Medicine, Volume 7, Issue 3, Page 283-296, June 2024.
Large animal models are essential for experimental progress in organ transplant procedures and donor organ interventions. This review provides a summary of two major organ donation procedures, a detailed methods description and pharmacopeia for these procedures, an overview of existing research progress in these areas, and our experience in potential ...
Frazer I. Heinis, Shaheed Merani, Nicholas W. Markin, Kim F. Duncan, Michael J. Moulton, Lance Fristoe, William E. Thorell, Raechel A. Sherrick, Tami R. Wells, Matthew T. Andrews, Marian Urban   +10 more
wiley   +1 more source

Beyond the Final Heartbeat: Neurological Perspectives on Normothermic Regional Perfusion for Organ Donation after Circulatory Death

Annals of Neurology, Volume 95, Issue 6, Page 1035-1039, June 2024.
Normothermic regional perfusion (NRP) has recently been used to augment organ donation after circulatory death (DCD) to improve the quantity and quality of transplantable organs. In DCD‐NRP, after withdrawal of life‐sustaining therapies and cardiopulmonary arrest, patients are cannulated onto extracorporeal membrane oxygenation to reestablish blood ...
Matthew P. Kirschen, Ariane Lewis, Michael A. Rubin, Panayiotis N. Varelas, David M. Greer   +4 more
wiley   +1 more source

Financial impact of donation after circulatory death heart transplantation: A single‐center analysis

Clinical Transplantation, Volume 38, Issue 4, April 2024.
Abstract Introduction Clinical success of donation after circulatory death (DCD) heart transplantation is leading to growing adoption of this technique. In comparison to procurement from a brain‐dead donor, DCD requires additional resources. The economic impact of DCD heart transplantation from the hospital perspective is not well known.
Marian Urban, Timothy R. Ryan, John Y. Um, Aleem Siddique, Anthony W. Castleberry, Brian D. Lowes   +5 more
wiley   +1 more source

Thoraco-abdominal normothermic regional perfusion does not restore cerebral blood flow or electrical activity despite collateral supra-aortic blood flow in a porcine model

JHLT Open
Background: It is unknown whether ligation of supra-aortic vessels during thoraco-abdominal normothermic regional perfusion (TA-NRP) can prevent postmortem brain function, ensuring the permanence of death.
Matthieu Glorion, MD MSc, Joel Neves Briard, MD MSc, Louise Roquebert, Sabina Pizzi, Ahmed Menaouar, PhD, Mélanie Borie, MSc, Manon Robert, MSc, Dang Khoa Nguyen, MD PhD, Michaël Chassé, MD PhD, Basil Nasir, MD, Pasquale Ferraro, MD, Shant Der Sarkissian, PhD, MBA, Pierre-Emmanuel Noly, MD PhD, Nicolas Noiseux, MD PhD   +13 more
doaj   +1 more source

Experiencia en DAC cardiaca en la Comunidad Valenciana: programa de extracción cardiaca extrahospitalaria

Cirugía Cardiovascular
Resumen: Introducción: En España desde el año 2020 se realizan trasplantes cardiacos de corazones obtenidos a partir de la donación en asistolia controlada (DAC). Mostramos nuestra experiencia desde el inicio del programa de DAC cardiacas.
Audelio Guevara-Bonilla, Eduardo Tébar-Botí, Claudia Aguirre-Ramón, Alexandra Merino-Orozco, Carlos Domínguez-Massa, Manuel Pérez-Guillén, Ana Bel-Mínguez, Salvador Torregrosa-Puerta, Tomás Heredia-Cambra, Alejandro Rincón-Almanza, María J. Dalmau-Sorli, Iván Martín González, Francisco J. Valera Martínez, Ana Tur-Alonso, Juan B. Martínez León   +14 more
doaj   +1 more source

Reply to: "Normothermic regional perfusion - What is the benefit?".

, 2019
Wethank Drs. Schlegel, Muiesan, and Dutkowski for their interest in our manuscript1 and are delighted to provide clearer and updated information regarding the use of normothermic regional perfusion (NRP) in controlled donation after circulatory death ...
Hessheimer, Amelia J, Ramirez, Pablo, Fundora-Suarez, Yiliam, Pardo, Fernando, Sanchez Turrion, Victor, Marin, Luis Miguel, Charco, Ramon, Gomez, Manuel, Gastaca, Mikel, Lopez-Baena, Jose Angel, Ruíz, Patricia, Parrilla, Pascual, Rodriguez, Juan Carlos, Pacheco, David, Llado, Laura, Rodríguez-Laiz, Gonzalo, Rivas, Jose Ignacio, Lopez-Andujar, Rafael, Villar, Jesus, Jimenez, Carlos, Coll, Elisabeth, Gomez-Bravo, Miguel Angel, Dominguez-Gil, Beatriz, Garcia-Valdecasas, Juan Carlos, Bosca, Andrea, Garcia-Sesma, Alvaro, Blanco, Gerardo, Santoyo, Julio, Sanchez, Belinda, Fondevila, Constantino, Lopez-Monclus, Javier, Briceño, Javier, Barrera, Manuel   +32 more
core   +1 more source

Use of ex vivo normothermic machine perfusion after normothermic regional perfusion to salvage a poorly perfused DCD kidney.

, 2020
Normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) have both been used in the procurement and conditioning of abdominal organs from donation after circulatory death donors with reported improved outcomes for the recipients ...

core   +2 more sources