Results 11 to 20 of about 163,928 (261)

Dysfunction of the Voltage‐Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe Brugada syndrome is an inherited cardiac arrhythmia associated with high risk of sudden death. Although 20% of patients with Brugada syndrome carry mutations in SCN5A, the molecular mechanisms underlying this condition are still largely ...
Vincent Portero, Solena Le Scouarnec, Zeineb Es‐Salah‐Lamoureux, Sophie Burel, Jean‐Baptiste Gourraud, Stéphanie Bonnaud, Pierre Lindenbaum, Floriane Simonet, Jade Violleau, Estelle Baron, Eléonore Moreau, Carol Scott, Stéphanie Chatel, Gildas Loussouarn, Thomas O'Hara, Philippe Mabo, Christian Dina, Hervé Le Marec, Jean‐Jacques Schott, Vincent Probst, Isabelle Baró, Céline Marionneau, Flavien Charpentier, Richard Redon   +23 more
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Feasibility of setting up a pre-operative optimisation ‘pre-hab’ service for lung cancer surgery in the UK

Perioperative Medicine, 2020
Pre-operative optimisation ‘pre-hab’ is a growing area in peri-operative medicine. This is usually undertaken with the aim of reducing post-operative complications.
William M. Ricketts, Karen Bollard, Emma Streets, Kristi Hutton, Catherine Hornby, Kelvin Lau   +5 more
doaj   +1 more source

Pathophysiology of light phenotype SARS-CoV-2 interstitial pneumonia: from histopathological features to clinical presentations

Pulmonology, 2022
Little is known about the light phenotype of SARS-CoV-2 pneumonia, which behaves in an unusual way, unlike other known respiratory diseases. We believe that the histopathological features of early COVID-19 could be considered the pathophysiological ...
S. Oldani, C. Ravaglia, S. Bensai, L. Bertolovic, C. Ghirotti, S. Puglisi, S. Martinello, F. Sultani, C. Colinelli, S. Piciucchi, S. Simoncelli, V. Poletti   +11 more
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A quality improvement program to reduce the time on the lung transplant waiting list at the Nantes University Hospital

Orphanet Journal of Rare Diseases, 2018
Background In 2010, the time on the lung transplant waiting list in Nantes University Hospital (NUH) was 9.2 months, compared to a French national median of about 4 months.
Isabelle Danner-Boucher, Véronique Loppinet, Aurore Boxus, Claire Dary, Anne Brigitte Lambert, Marine Prieur, Céline Vallet, Adrien Tissot   +7 more
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The Morphological Transformation of the Thorax during the Eclosion of Drosophila melanogaster (Diptera: Drosophilidae)

Insects, 2023
The model organism Drosophila melanogaster, as a species of Holometabola, undergoes a series of transformations during metamorphosis. To deeply understand its development, it is crucial to study its anatomy during the key developmental stages.
Si-Pei Liu, Hao-Dong Yin, Wen-Jie Li, Zhuang-Hui Qin, Yi Yang, Zheng-Zhong Huang, Le Zong, Xiao-Kun Liu, Zhong Du, Wei-Li Fan, Ya-Qiong Zhang, Dan Zhang, Yong E. Zhang, Xing-Yue Liu, Ding Yang, Si-Qin Ge   +15 more
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The IL-15 / sIL-15Rα complex modulates immunity without effect on asthma features in mouse

Respiratory Research, 2020
Background Interleukin 15 (IL-15) is a growth and modulating factor for B, T lymphocytes and natural killer cells (NK). Its action on innate and adaptive immunity is modulated by its alpha chain receptor (IL-15Rα).
Antoine Moui, Martin Klein, Dorian Hassoun, Eléonore Dijoux, Marie-Aude Cheminant, Antoine Magnan, Grégory Bouchaud   +6 more
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Flight performance of pollen starved honey bees and incomplete compensation through ingestion after early life pollen deprivation

Frontiers in Physiology, 2022
We investigated the effect of adult honey bee pollen nutrition on the flight performance of honey bees. Therefore, caged bees were allowed to perform 30 min of defecation/training flights every second day before flight performance of pollen-fed bees and ...
Robert Brodschneider, Eslam Omar, Eslam Omar, Karl Crailsheim   +3 more
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Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia

Disease Models & Mechanisms, 2016
Proprotein convertase subtilisin kexin type 9 (PCSK9) is a critical modulator of cholesterol homeostasis. Whereas PCSK9 gain-of-function (GOF) mutations are associated with autosomal dominant hypercholesterolemia (ADH) and premature atherosclerosis ...
Karim Si-Tayeb, Salam Idriss, Benoite Champon, Amandine Caillaud, Matthieu Pichelin, Lucie Arnaud, Patricia Lemarchand, Cédric Le May, Kazem Zibara, Bertrand Cariou   +9 more
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The Brugada syndrome: a rare arrhythmia disorder with complex inheritance

Frontiers in Cardiovascular Medicine, 2016
For the last ten years, applying new sequencing technologies to thousands of whole exomes has revealed the high variability of the human genome. Extreme caution should thus be taken to avoid misinterpretation when associating rare genetic variants to ...
Jean-Baptiste eGourraud, Jean-Baptiste eGourraud, Jean-Baptiste eGourraud, Jean-Baptiste eGourraud, Julien eBarc, Julien eBarc, Julien eBarc, Aurélie eThollet, Solena eLe Scouarnec, Solena eLe Scouarnec, Solena eLe Scouarnec, Hervé eLe Marec, Hervé eLe Marec, Hervé eLe Marec, Hervé eLe Marec, Jean-Jacques eSchott, Jean-Jacques eSchott, Jean-Jacques eSchott, Richard eRedon, Richard eRedon, Richard eRedon, Vincent eProbst, Vincent eProbst, Vincent eProbst, Vincent eProbst   +24 more
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Familial screening in case of acute myocarditis reveals inherited arrhythmogenic left ventricular cardiomyopathies

ESC Heart Failure, 2020
Aims Several data suggest that acute myocarditis could be related to genetic variants involved in familial cardiomyopathies, particularly arrhythmogenic cardiomyopathy, but the management of patients with acute myocarditis and their families regarding ...
Nicolas Piriou, Lara Marteau, Florence Kyndt, Jean Michel Serfaty, Claire Toquet, Laurianne Le Gloan, Karine Warin‐Fresse, Damien Guijarro, Thierry Le Tourneau, Emilie Conan, Aurélie Thollet, Vincent Probst, Jean‐Noël Trochu   +12 more
doaj   +1 more source