Results 11 to 20 of about 377,719 (259)

Dysfunction of the Voltage‐Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe Brugada syndrome is an inherited cardiac arrhythmia associated with high risk of sudden death. Although 20% of patients with Brugada syndrome carry mutations in SCN5A, the molecular mechanisms underlying this condition are still largely ...
Vincent Portero, Solena Le Scouarnec, Zeineb Es‐Salah‐Lamoureux, Sophie Burel, Jean‐Baptiste Gourraud, Stéphanie Bonnaud, Pierre Lindenbaum, Floriane Simonet, Jade Violleau, Estelle Baron, Eléonore Moreau, Carol Scott, Stéphanie Chatel, Gildas Loussouarn, Thomas O'Hara, Philippe Mabo, Christian Dina, Hervé Le Marec, Jean‐Jacques Schott, Vincent Probst, Isabelle Baró, Céline Marionneau, Flavien Charpentier, Richard Redon   +23 more
doaj   +1 more source

Pathophysiology of light phenotype SARS-CoV-2 interstitial pneumonia: from histopathological features to clinical presentations

Pulmonology, 2022
Little is known about the light phenotype of SARS-CoV-2 pneumonia, which behaves in an unusual way, unlike other known respiratory diseases. We believe that the histopathological features of early COVID-19 could be considered the pathophysiological ...
S. Oldani, C. Ravaglia, S. Bensai, L. Bertolovic, C. Ghirotti, S. Puglisi, S. Martinello, F. Sultani, C. Colinelli, S. Piciucchi, S. Simoncelli, V. Poletti   +11 more
doaj   +1 more source

Increasing prevalence of asthma diagnosis and symptoms in children is confined to mild symptoms [PDF]

, 2001
BACKGROUND: The prevalence of childhood asthma is increasing but few studies have investigated trends in asthma severity. We investigated trends in asthma diagnosis and symptom morbidity between an eight year time period in a paired prevalence study.
Billings, C., Das, C., Duggan, R., Ng Man Kwong, G., Powell, C.V.E., Primhak, R.A., Proctor, A., Whyte, M.K.B.   +7 more
core   +2 more sources

Feasibility of setting up a pre-operative optimisation ‘pre-hab’ service for lung cancer surgery in the UK

Perioperative Medicine, 2020
Pre-operative optimisation ‘pre-hab’ is a growing area in peri-operative medicine. This is usually undertaken with the aim of reducing post-operative complications.
William M. Ricketts, Karen Bollard, Emma Streets, Kristi Hutton, Catherine Hornby, Kelvin Lau   +5 more
doaj   +1 more source

A quality improvement program to reduce the time on the lung transplant waiting list at the Nantes University Hospital

Orphanet Journal of Rare Diseases, 2018
Background In 2010, the time on the lung transplant waiting list in Nantes University Hospital (NUH) was 9.2 months, compared to a French national median of about 4 months.
Isabelle Danner-Boucher, Véronique Loppinet, Aurore Boxus, Claire Dary, Anne Brigitte Lambert, Marine Prieur, Céline Vallet, Adrien Tissot   +7 more
doaj   +1 more source

Real-time simulation of three-dimensional shoulder girdle and arm dynamics [PDF]

, 2014
Electrical stimulation is a promising technology for the restoration of arm function in paralyzed individuals. Control of the paralyzed arm under electrical stimulation, however, is a challenging problem that requires advanced controllers and command ...
Blana, D, Chadwick, EK, Kirsch, RF, van den Bogert, AJ   +3 more
core   +3 more sources

The IL-15 / sIL-15Rα complex modulates immunity without effect on asthma features in mouse

Respiratory Research, 2020
Background Interleukin 15 (IL-15) is a growth and modulating factor for B, T lymphocytes and natural killer cells (NK). Its action on innate and adaptive immunity is modulated by its alpha chain receptor (IL-15Rα).
Antoine Moui, Martin Klein, Dorian Hassoun, Eléonore Dijoux, Marie-Aude Cheminant, Antoine Magnan, Grégory Bouchaud   +6 more
doaj   +1 more source

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]

, 2018
BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.

core   +2 more sources

The effects of disruptive and stabilizing selection on body size in Drosophila melanogaster. III. Genetic analysis of two lines with different reactions to disruptive selection with mating of opposite extremes [PDF]

, 1974
A genetic analysis was made of two lines which when subjected to disruptive selection with compulsary mating of opposite extremes (D−) showed a different response viz.
Bos, M., Scharloo, W.
core   +3 more sources

The Morphological Transformation of the Thorax during the Eclosion of Drosophila melanogaster (Diptera: Drosophilidae)

Insects, 2023
The model organism Drosophila melanogaster, as a species of Holometabola, undergoes a series of transformations during metamorphosis. To deeply understand its development, it is crucial to study its anatomy during the key developmental stages.
Si-Pei Liu, Hao-Dong Yin, Wen-Jie Li, Zhuang-Hui Qin, Yi Yang, Zheng-Zhong Huang, Le Zong, Xiao-Kun Liu, Zhong Du, Wei-Li Fan, Ya-Qiong Zhang, Dan Zhang, Yong E. Zhang, Xing-Yue Liu, Ding Yang, Si-Qin Ge   +15 more
doaj   +1 more source