Results 31 to 40 of about 288,531 (350)

Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia

Disease Models & Mechanisms, 2016
Proprotein convertase subtilisin kexin type 9 (PCSK9) is a critical modulator of cholesterol homeostasis. Whereas PCSK9 gain-of-function (GOF) mutations are associated with autosomal dominant hypercholesterolemia (ADH) and premature atherosclerosis ...
Karim Si-Tayeb, Salam Idriss, Benoite Champon, Amandine Caillaud, Matthieu Pichelin, Lucie Arnaud, Patricia Lemarchand, Cédric Le May, Kazem Zibara, Bertrand Cariou   +9 more
doaj   +1 more source

Flight performance of pollen starved honey bees and incomplete compensation through ingestion after early life pollen deprivation

Frontiers in Physiology, 2022
We investigated the effect of adult honey bee pollen nutrition on the flight performance of honey bees. Therefore, caged bees were allowed to perform 30 min of defecation/training flights every second day before flight performance of pollen-fed bees and ...
Robert Brodschneider, Eslam Omar, Eslam Omar, Karl Crailsheim   +3 more
doaj   +1 more source

Atorvastatin as a stable treatment in bronchiectasis:a randomised controlled trial [PDF]

, 2014
Background: Bronchiectasis is characterised by chronic cough, sputum production, and recurrent chest infections. Pathogenesis is poorly understood, but excess neutrophilic airway inflammation is seen.
John W Govan, Davidson, Donald J, Harley, Catherine, Donald J Davidson, Graham, Catriona, Rossi, Adriano G, Hill, Adam T, Hill, Adam T., Mandal, Pallavi, Catherine Doherty, Manjit K Sidhu, Sidhu, Manjit K., Chalmers, James D., Catherine Harley, Pallavi Mandal, James D Chalmers, Govan, John W, Doherty, Catherine, Chalmers, James D, Govan, John W., Sethi, Tariq, Rossi, Adriano G., Adam T Hill, Sidhu, Manjit K, Adriano G Rossi, Davidson, Donald J., Catriona Graham, Tariq Sethi   +27 more
core   +1 more source

The Brugada syndrome: a rare arrhythmia disorder with complex inheritance

Frontiers in Cardiovascular Medicine, 2016
For the last ten years, applying new sequencing technologies to thousands of whole exomes has revealed the high variability of the human genome. Extreme caution should thus be taken to avoid misinterpretation when associating rare genetic variants to ...
Jean-Baptiste eGourraud, Jean-Baptiste eGourraud, Jean-Baptiste eGourraud, Jean-Baptiste eGourraud, Julien eBarc, Julien eBarc, Julien eBarc, Aurélie eThollet, Solena eLe Scouarnec, Solena eLe Scouarnec, Solena eLe Scouarnec, Hervé eLe Marec, Hervé eLe Marec, Hervé eLe Marec, Hervé eLe Marec, Jean-Jacques eSchott, Jean-Jacques eSchott, Jean-Jacques eSchott, Richard eRedon, Richard eRedon, Richard eRedon, Vincent eProbst, Vincent eProbst, Vincent eProbst, Vincent eProbst   +24 more
doaj   +1 more source

Familial screening in case of acute myocarditis reveals inherited arrhythmogenic left ventricular cardiomyopathies

ESC Heart Failure, 2020
Aims Several data suggest that acute myocarditis could be related to genetic variants involved in familial cardiomyopathies, particularly arrhythmogenic cardiomyopathy, but the management of patients with acute myocarditis and their families regarding ...
Nicolas Piriou, Lara Marteau, Florence Kyndt, Jean Michel Serfaty, Claire Toquet, Laurianne Le Gloan, Karine Warin‐Fresse, Damien Guijarro, Thierry Le Tourneau, Emilie Conan, Aurélie Thollet, Vincent Probst, Jean‐Noël Trochu   +12 more
doaj   +1 more source

A Novel Approach for Multi-Label Chest X-Ray Classification of Common Thorax Diseases

IEEE Access, 2019
Chest X-ray (CXR) is one of the most common types of radiology examination for the diagnosis of thorax diseases. Computer-aided diagnosis (CAD) was developed to help radiologists to achieve diagnostic excellence in a short period of time and to enhance ...
I. Allaouzi, M. Ben Ahmed
semanticscholar   +1 more source

THORAX AND ABDOMEN [PDF]

Annals of Surgery, 1894
n ...
openaire   +1 more source

Osteopontin as a Link between Inflammation and Cancer: The Thorax in the Spotlight

Cells, 2019
The glycoprotein osteopontin (OPN) possesses multiple functions in health and disease. To this end, osteopontin has beneficial roles in wound healing, bone homeostasis, and extracellular matrix (ECM) function.
A. Lamort, I. Giopanou, I. Psallidas, G. Stathopoulos   +3 more
semanticscholar   +1 more source

Effect of diet on asthma and allergic sensitisation in the International Study on Allergies and Asthma in Childhood (ISAAC) Phase Two

, 2010
Background: The increasing prevalence of asthma and allergy might be related to diet, particularly in Western countries. A study was undertaken to assess the association between dietary factors, asthma and allergy in a large international study including
Garcia-Marcos L, Strachan D.P, Nagel G, Weinmayr G, ISAAC Phase Two Study Group, Kleiner A   +5 more
core   +1 more source

FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach

Radiation Oncology
FLASH therapy is a treatment technique in which radiation is delivered at ultra-high dose rates (≥ 40 Gy/s). The first-in-human FAST-01 clinical trial demonstrated the clinical feasibility of proton FLASH in the treatment of extremity bone metastases ...
E. Daugherty, Y. Zhang, Z. Xiao, A. Mascia, M. Sertorio, J. Woo, C. McCann, Kj Russell, RA Sharma, D. Khuntia, J. Bradley, C. Simone, JC Breneman, JP Perentesis   +13 more
semanticscholar   +1 more source