Results 21 to 30 of about 377,719 (259)

Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia

open access: yesDisease Models & Mechanisms, 2016
Proprotein convertase subtilisin kexin type 9 (PCSK9) is a critical modulator of cholesterol homeostasis. Whereas PCSK9 gain-of-function (GOF) mutations are associated with autosomal dominant hypercholesterolemia (ADH) and premature atherosclerosis ...
Karim Si-Tayeb   +9 more
doaj   +1 more source

Correspondence: British Thoracic Society guideline on pulmonary rehabilitation in adults: Does objectivity have a sliding scale? [PDF]

open access: yes, 2014
This article is made available through the Brunel Open Access Publishing Fund. Copyright © 2014 BMJ Publishing Group Ltd & British Thoracic Society. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non ...
Alison K McConnell   +5 more
core   +2 more sources

Familial screening in case of acute myocarditis reveals inherited arrhythmogenic left ventricular cardiomyopathies

open access: yesESC Heart Failure, 2020
Aims Several data suggest that acute myocarditis could be related to genetic variants involved in familial cardiomyopathies, particularly arrhythmogenic cardiomyopathy, but the management of patients with acute myocarditis and their families regarding ...
Nicolas Piriou   +12 more
doaj   +1 more source

Flight performance of pollen starved honey bees and incomplete compensation through ingestion after early life pollen deprivation

open access: yesFrontiers in Physiology, 2022
We investigated the effect of adult honey bee pollen nutrition on the flight performance of honey bees. Therefore, caged bees were allowed to perform 30 min of defecation/training flights every second day before flight performance of pollen-fed bees and ...
Robert Brodschneider   +3 more
doaj   +1 more source

Immature stages of some eastern Nearctic Tabanidae (Diptera). IX. Chrysops beameri Brennan and Hybomitra trispila (Wiedemann) [PDF]

open access: yes, 2013
The larvae and pupae of two species of Tabanidae (Diptera), Chrysops beameri Brennan and Hybomitra trispila (Wiedemann), are described and illustrated, and their similarities and differences relative to similar species are discussed.
Goodwin, James. T.
core   +2 more sources

The Brugada syndrome: a rare arrhythmia disorder with complex inheritance

open access: yesFrontiers in Cardiovascular Medicine, 2016
For the last ten years, applying new sequencing technologies to thousands of whole exomes has revealed the high variability of the human genome. Extreme caution should thus be taken to avoid misinterpretation when associating rare genetic variants to ...
Jean-Baptiste eGourraud   +24 more
doaj   +1 more source

Hesperiidae of Rondônia, Brazil: Porphyrogenes Watson (Lepidoptera: Pyrginae: Eudamini), with descriptions of new species from Central and South America [PDF]

open access: yes, 2008
The pyrgine genus Porphyrogenes Watson, 1893 (Hesperiidae) is discussed, especially as it occurs in central Rondônia, Brazil. Of eleven species of Porphyrogenes found in Rondônia, four (P. specularis, P. convexus, P. sparus, and P.
Austin, George T.   +1 more
core   +1 more source

Mid-regional pro-atrial natriuretic peptide and copeptin as indicators of disease severity and therapy response in CTEPH

open access: yesERJ Open Research, 2020
Background Chronic thromboembolic pulmonary hypertension (CTEPH) leads to right heart failure. Pulmonary endarterectomy (PEA) or balloon pulmonary angioplasty (BPA) restore pulmonary haemodynamics and allow cardiac recovery.
Steffen D. Kriechbaum   +14 more
doaj   +1 more source

Standard methods for Apis mellifera anatomy and dissection [PDF]

open access: yes, 2013
An understanding of the anatomy and functions of internal and external structures is fundamental to many studies on the honey bee Apis mellifera. Similarly, proficiency in dissection techniques is vital for many more complex procedures.
CASAGRANDE-JALORETTO D C   +9 more
core   +1 more source

Modular proteins from the Drosophila sallimus (sls) gene and their expression in muscles with different extensibility [PDF]

open access: yes, 2007
The passive elasticity of the sarcomere in striated muscle is determined by large modular proteins, such as titin in vertebrates. In insects, the function of titin is divided between two shorter proteins, projectin and sallimus (Sls), which are the ...
Ayme-Southgate   +53 more
core   +1 more source

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