Results 221 to 230 of about 1,449,742 (274)

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

Advanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim, Na Yeon Han, Ayman Muzammal, Jae Hun Ahn, Changkeun Im, Sujin Kim, Sairan Eom, Choong Mo Kang, Ku Kang, Yong Jin Lee, Kyo Chul Lee, Michael K. Schultz, Dongyoul Lee   +12 more
wiley   +1 more source

Fluorite and rare-metals mineralization in greisenized granite of Um Naggat area, Egypt constrained by physical separation and beneficiation assessment. [PDF]

Sci Rep
Fawzy MM, Diab M, Abdel Gawad AE.
europepmc   +1 more source

SpaCut: Transcript‐Aware Morphology Fusion for Robust Cell Segmentation in Subcellular Spatial Transcriptomics

Advanced Science, EarlyView.
Subcellular spatial transcriptomics enables high‐resolution mapping of gene expression within tissues, but accurate cell segmentation is essential for assigning transcripts to individual cells. We present SpaCut, a deep learning framework that integrates transcriptomic features with nucleus‐guided morphological information to precisely delineate cell ...
Yongheng Li, Fangfang Zhu, Wenwen Min
wiley   +1 more source

CMPO-Functionalized Silica Sorbents for pH-Tunable Separation and Enrichment of Rare-Earth Elements from Environmental Matrices. [PDF]

ACS Sustain Chem Eng
Sakr AK, Praneeth S, Roy PK, Dittrich TM.   +3 more
europepmc   +1 more source

Combined Immune‐Peptide Nanofiber with HSP70/AKT/mTOR Axis Blockade Enhances Photothermal Immunotherapy, Inhibiting Tumor Growth and Recurrence

Advanced Science, EarlyView.
A carrier‐free peptide‐guided PSP@IR‐CF3 nanofiber system integrates PD‐L1 targeting and photothermal immunotherapy for enhanced cancer treatment. By revealing PTIT‐induced activation of the HSP70/AKT/mTOR pathway and incorporating mTOR inhibition, this strategy effectively overcomes therapeutic resistance and prevents tumor recurrence, providing a ...
Xinyu Zhang, Zhenqi Jiang, Wenjia Zhang, Juncheng Wu, Haozhuo Guo, Changlei Li, Mingwei Sun, Xiaoying Tang, Yue Zhang, Wei Huang, Huadan Xue, Yang Du   +11 more
wiley   +1 more source

The implementation of the urinalysis method for ²¹⁰Po monitoring of employees in the selected industrial sector operating with NORMs in Poland. [PDF]

Int J Occup Med Environ Health
Rzemek K, Dymecka M.
europepmc   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source

Ratiometric discrimination of Th⁴⁺ ions by a fluorogenic quinoline appended phenanthridine sensor and its applications. [PDF]

RSC Adv
Manoj Kumar S, Munusamy S, Enbanathan S, Ranganadin S, Kulathu Iyer S.   +4 more
europepmc   +1 more source

Adaptive Active Illumination Via Translationally and Axially Tunable Cascaded Metasurfaces

Advanced Science, EarlyView.
Active three‐dimensional sensing faces a fundamental trade‐off between seeing farther and covering more of the scene. Translationally and axially tunable cascaded metasurfaces overcome this limitation by continuously adapting beam direction and illumination coverage.
Chi Zhang, Jianing Yang, Lingyun Zhang, Jingyu Bao, Bingbai Li, Qingsong Feng, Rui You, Xiaoli Jing, Fei Xing, Xiaoguang Zhao, Zheng You   +10 more
wiley   +1 more source

Lanthanide Content and Adulteration Testing of Greek Honeydew and Nectar Honey. [PDF]

Molecules
Mazarakioti EC, Karabagias VK, Karabournioti S, Lazaridis DG, Zotos A, Patakas A, Ladavos A, Karabagias IK.   +7 more
europepmc   +1 more source