Results 41 to 50 of about 4,218 (238)

“Clinical and diagnostic value of GDF-15 and β-hCG in first trimester pregnancy with threatened miscarriage and the short-term impact of hormonal support: a prospective study”

Middle East Fertility Society Journal
Background Threatened miscarriage affects pregnancies globally, necessitating reliable diagnostic markers. Growth differentiation factor 15 (GDF-15) is associated with adverse pregnancy outcomes, yet its diagnostic value and response to progesterone ...
Fares Najah Abd, Rusul Arif Abd Ali
doaj   +1 more source

Maternal and Neonatal Complications Associated with Breast Cancer Systemic Treatments—A VigiBase Disproportionality Analysis Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Rayan Kabirian, Floriane Jochum, Elise Dumas, Florence Coussy, Kevin Bihan, Bénédicte Lebrun‐Vignes, Barbara Pistilli, Marc‐Antoine Benderra, Lise Selleret, Laurent Chouchana, Fabien Reyal, Anne‐Sophie Hamy, Paul Gougis   +12 more
wiley   +1 more source

Laboratory criteria for early threatened miscarriage

Health and Ecology Issues, 2022
Objective. To determine the role of placental growth factor, fibronectin, certain hemostatic parameters and glycodelin in the genesis of early miscarriage.Materials and methods. Venous blood, inpatient medical records (form No.003/u-07), prenatal records (form No.113/u-07) of 94 pregnant women. The software package "Statistica" 10.0 and the programming
L. V. Kastsova, L. V. Gutikova, M. N. Kurbat, V. R. Shulika, A. Z. Kastsova   +4 more
openaire   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

First-Trimester Threatened Abortion: Can Red Blood Cell Distribution Width-Standard Deviation Predict Miscarriage?

Gynecology Obstetrics & Reproductive Medicine
OBJECTIVE: The objective of the study was to investigate the predictive value of red blood cell distribution width-standard deviation (RDW-SD) and another complete blood count (CBC) derived blood markers in patients presenting with threatened abortion ...
Sebnem Karagun, Yusuf Dal, Hamza Yildiz, Sefanur Gamze Karaca, Ahmet Zeki Nessar, Ayhan Coskun   +5 more
doaj   +1 more source

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

Clinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu, Zhigang Liu, Xiaohu Kuang, Yueming Wang, Xiaoyi Liu, Jiyuan Ding, Xia Zhou, Xin Zhou, Qianyu Liang, Meizhuo Zhang, Hao Zhao, Qingqing Tan, Weihong Zheng, Huaxin Liao, Charlotte Lemech, Wanmei Wang   +15 more
wiley   +1 more source

Prescriptions for seizure cluster rescue therapy are not associated with decreased pediatric ED utilization

Epilepsia Open, EarlyView.
Abstract Objective Seizure clusters, or acute repetitive seizures, are a phenomenon often experienced by patients with epilepsy and pose a significant treatment challenge for clinicians. Several rescue medications have been approved by the Food and Drug Administration for the treatment of seizure clusters – including diazepam rectal gel, intranasal ...
Sarah A. Mangold, Mariah Eisner, Gabrielle Brown‐Mitchell, Christopher W. Beatty, Stephanie M. Ahrens, Jamie E. Twanow, Adam P. Ostendorf   +6 more
wiley   +1 more source

Embodied attachments: IVF, the maternal body, and the making of embryo kinship

Feminist Anthropology, EarlyView.
Abstract Within the sphere of IVF (in vitro fertilization), there is increasing concern about the stockpiles of frozen embryos held in clinics across the country. This normative discourse tends to take the patient‐embryo relationship for granted, with salient political consequences for current embryo ‘personhood’ debates.
Manon Lefevre
wiley   +1 more source

THREATENED ABORTION: A RISK FACTOR FOR POOR PREGNANCY OUTCOME [PDF]

Acta Medica Iranica, 2008
The scientific literature regarding threatened abortion is relatively limited on the subject of outcomes and viability at term. To investigate prospectively the risk of adverse pregnancy outcome in women presenting with first-trimester threatened ...
F Davari-Tanha, M Shariat, M Kaveh, M Ebrahimi, S Jalalvand   +4 more
doaj   +1 more source

Spontaneous hemoperitoneum in a 29‐week pregnancy with a history of endometriosis: A case report and review of the literature

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 31-37, April 2025.
Abstract Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births. Although seen rarely, it is associated with perinatal morbidity and mortality due to maternal hemodynamic instability ...
Shamsi Mehdiyev, Fatma Basak Tanoglu, Esma Demir Altuncu, Engin Oral   +3 more
wiley   +1 more source