Results 51 to 60 of about 1,518,426 (249)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Designing the image integrated between real reality and holography

Maǧallaẗ Al-Turāṯ wa Al-Taṣmīm
Three-dimensional holographic display technology is a sign of future technology and communications. This technology received global attention for the first time in 2008 when first time as a hologram with the aim of reducing the environmental impact of ...
Prof. Dr. Safwat Abdel Halim Prof. Dr. Wael Mohamed Anani Shehab Muhammad Jamal al-Din Qayati
doaj   +1 more source

Three Dimensional Spheroid Co-culture Invasion Assay

Bio-Protocol, 2015
The assay was developed to investigate the impact of stromal cells of different types (in our case breast cancer associated fibroblasts stably manipulated to modify expression of genes of interest) on the invasive capacity of epithelial cancer cells (in ...
Eldo Verghese, Eldo Verghese
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

A scoping review on the potential of three-dimensional bioprinting in auricular cartilage regeneration

SRM Journal of Research in Dental Sciences
Background The human ear significantly influences facial appearance. Auricular abnormalities can arise from many causes, and the cartilage cannot self-regenerate.
Eman Assem Ibrahim, Moamen Mohsen Sarhan, Salah Ezzelarab, Mona K. Marei   +3 more
doaj   +1 more source

Jitter Elimination in Shape Recovery by using Adaptive Neural Network Filter

Sensors, 2019
Three-dimensional (3D) cameras are expensive because they employ additional charged coupled device sensors and optical elements, e.g., lasers or complicated scanning mirror systems.
Sung-An Lee, Hoon-Seok Jang, Byung-Geun Lee   +2 more
doaj   +1 more source

Comparative Analysis of Object Digitization Techniques Applied to the Characterization of Deformed Materials in Ballistic Tests

Sensors, 2020
Several three-dimensional scanning methods have been developed and improved over the past 40 years. The peculiarities of each technique, associated with the computational advances of the period, allowed the increasing application and diffusion of the ...
Filipe Dmengeon Pedreiro Balbino, Khrissy Aracélly Reis Medeiros, Carlos Roberto Hall Barbosa   +2 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Surface Scanning-Based Texture Atlas for Voxelized 3D Object

IEEE Access, 2020
The representation of voxel colors has become crucial because voxelized 3D data are used in a variety of applications. In particular, texture atlases are widely used for representing voxel colors.
Tae Young Jang, Seong Dae Kim, Sung Soo Hwang   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source