Results 61 to 70 of about 12,593,924 (215)

Effects of Biotin on a Fluorescein‐Based Photosensitizer Revealed by Multiscale Computational Modeling

Chemistry – A European Journal, EarlyView.
Biotinylation of a fluorescein‐based photosensitizer enhances its performance in PDT through a synergistic dual action. In addition to Type II singlet oxygen generation common to both dyes, the biotinylated system induces stronger membrane perturbation and higher local accumulation in lipid membranes, associated with increased water permeability and ...
Valeria Butera, Alessandra Gilda Ritacca, Giampaolo Barone, Nino Russo, Marta Erminia Alberto   +4 more
wiley   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Elective irradiation of the neck : a three-dimensional CT definition of the target for conformal radiotherapy [PDF]

, 1997
When no lymph node metastases are detected clinically in patients with head and neck cancer, the neck is staged as NO. The elective treatment of the NO neck, by either surgery or radiotherapy, results in excellent local control rates.
Nowak, P.J.C.M. (Peter), Nowak, Peter
core   +1 more source

Automated B‐cell and plasma cell identification using unsupervised clustering by FlowSOM and an excel‐based classification model

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Manual gating for plasma cell (PC) identification in multiparametric flow cytometry (MFC) is time‐consuming and operator‐dependent, especially when PCs are scarce. Artificial intelligence approaches such as unsupervised clustering (e.g., FlowSOM) map high‐dimensional data that still require expert interpretation.
Ethan James Gantana, Ernest Musekwa, Erica‐Mari Nell, Zivanai Cuthbert Chapanduka   +3 more
wiley   +1 more source

Sustainable plant‐leaf‐derived carbon dots with deep‐red emission enable 1‐min photodynamic therapy of tumors

FlexMat, EarlyView.
In this study, plant‐derived carbon dots (CDs) were prepared using natural plant leaves as raw materials through solvothermal method. These CDs retain the porphyrin structure from chlorophyll and can simultaneously generate I and II types of reactive oxygen species. A 660 nm laser irradiation for only 1 min can achieve efficient photodynamic anti‐tumor
Renjing Chen, Danjie Han, Zemin Wang, Xinyi Lu, Peng He, Lili Hou, Chuantong Cheng, Xueting Liu, Jinli Liu, Zhiming Wang, Zongwen Liu, Xingtao Zhou, Zichao Luo, Kebin Lin   +13 more
wiley   +1 more source

Treatment of optic nerve sheath meningioma with three-dimensional conformal radiation

, 2000
PURPOSE: To report a patient recovering vision after three-dimensional conformal radiotherapy for optic nerve sheath meningioma. METHODS: Radiotherapy was delivered by a three-dimensional conformal technique in 28-180-cGy fractions.
Breneman, J, Moyer, P D, Golnik, K C
core   +1 more source

Recent advances in radiotherapy

BMC Medicine, 2010
Radiation therapy has come a long way from treatment planning based on orthogonal radiographs with large margins around tumours. Advances in imaging and radiation planning software have led to three-dimensional conformal radiotherapy and, further, to ...
Nutting CM, Bhide SA
doaj   +1 more source

Second Breast‐Conserving Treatment for Ipsilateral Breast Tumor Recurrence: A Review of Patient Selection, Reirradiation Techniques, and Clinical Outcomes

International Journal of Cancer, EarlyView.
ABSTRACT Local recurrence after primary breast cancer treatment remains a complex clinical scenario in patients previously treated with breast‐conserving therapy and radiotherapy. For decades, salvage mastectomy was considered the standard treatment for ipsilateral breast tumor recurrence, largely because of concerns about local control after repeat ...
Cezara Cheptea, Youlia Kirova, Radu Iulian Mitrica, Mihaela Badea, Pierre Loap   +4 more
wiley   +1 more source

A novel inverse optimization based three-dimensional conformal radiotherapy technique in craniospinal irradiation.

, 2021
Our aim was to develop a novel inverse optimization-based three-dimensional conformal radiotherapy (i3DCRT) technique for craniospinal irradiation. The imaging data of 20 patients with medulloblastoma were used retrospectively.
Ozyigit, Gokhan, Biltekin, FATİH, Yazici, GÖZDE   +2 more
core   +1 more source

Evaluation of Testis as Organ at Risk in Carcinoma Rectum with Various Radiotherapy Delivery Techniques [PDF]

Middle East Journal of Cancer
Background: Due to the close approximation of testis to radiotherapy treatment field in male carcinoma rectum patients, it receives either scattered or direct radiation.
Poornachandra Tejaswi Siddappa, Shamsundar Sunkappa, Vinay Desai, Jagannath Kunigal Puttaswamy, Nanda Ramanand, Aradhana Katke, Thejaswini Boraiah   +6 more
doaj   +1 more source