Results 31 to 40 of about 23,328 (266)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Three Dimensional Analysis Of Non-Planar Crack Propagation Problems

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi, 2017
Energy, defence, aeronautics and space technologies are critical for countries and they are the leading areas which promote and require development of science and technology.
Oğuzhan DEMİR, Ali Osman AYHAN
doaj  

Three‐dimensional crack monitoring by electrical resistivity measurement [PDF]

open access: yesEuropean Journal of Soil Science, 2004
Summary Soil cracks formed by natural processes play a key role in water and gas transfer. Patterns of soil cracks are, however, difficult to characterize. Our aim here is to assess the effectiveness of three‐dimensional electrical resistivity surveys in detecting soil crack networks.
Samouëlian, Anatja   +5 more
openaire   +3 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

THE THREE DIMENSIONAL CURVED ELASTICITY-PLASTICITY CRACK TIP OPENING DISPLACEMENT UNDER QUASI-STATIC LOAD

open access: yesJixie qiangdu, 2019
In this article, three dimensional elastic-plastic curved crack tip opening displacement under quasi-static loads has been mainly studied, and three dimensional curved crack tip opening displacement has been calculated as a practical application of a ...
YANG DaPeng   +4 more
doaj  

Full-Field Strain Characterizations and Fracture Process of Rock Blasting Using a Small-Scale Double-Hole Bench Model

open access: yesAdvances in Civil Engineering, 2020
A small-scale double-hole bench model is designed with granite to study the fracture mechanism of rock blasting. By combining high-speed camera and digital image correlation, the full-field strain characterization and fracture process of the specimen ...
Jun Yang   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

PLASTICITY AREA AT THE THREE DIMENSIONAL CURVED ELASTICITY-PLASTICITY CRACK TIP UNDER QUASI-STATIC LOAD

open access: yesJixie qiangdu, 2018
In this article,three dimensional elastic-plastic curved crack tip plasticity area under quasi-static loads has been mainly studied,and three dimensional curved crack tip plasticity area has been calculated as a practical application of a second order ...
YANG DaPeng   +3 more
doaj  

Evaluation of Fatigue Crack Front Shape for a Specimen with Finite Thickness

open access: yesMATEC Web of Conferences, 2015
Two-dimensional elastic or elasto-plastic models dominate the current fatigue crack growth assessment and life prediction procedures for plate components with through-the-thickness cracks.
He Zhuang   +2 more
doaj   +1 more source

Fatigue assessment and crack propagation of floorbeam cutout in orthotropic bridge decks

open access: yesMaterials & Design, 2023
Based on the fatigue cracking of floorbeam cutout in a bridge, the field testing under random traffic flows was firstly conducted to investigate the fatigue crack initiation, and then a multi-scale numerical model, based on extended finite element method
Ze Xiang, Zhiwen Zhu, Xinbin Lei
doaj   +1 more source

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