Results 41 to 50 of about 22,441 (265)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Three Dimensional Analysis Of Non-Planar Crack Propagation Problems

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi, 2017
Energy, defence, aeronautics and space technologies are critical for countries and they are the leading areas which promote and require development of science and technology.
Oğuzhan DEMİR, Ali Osman AYHAN
doaj  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

THE THREE DIMENSIONAL CURVED ELASTICITY-PLASTICITY CRACK TIP OPENING DISPLACEMENT UNDER QUASI-STATIC LOAD

open access: yesJixie qiangdu, 2019
In this article, three dimensional elastic-plastic curved crack tip opening displacement under quasi-static loads has been mainly studied, and three dimensional curved crack tip opening displacement has been calculated as a practical application of a ...
YANG DaPeng   +4 more
doaj  

Three‐dimensional crack monitoring by electrical resistivity measurement [PDF]

open access: yesEuropean Journal of Soil Science, 2004
Summary Soil cracks formed by natural processes play a key role in water and gas transfer. Patterns of soil cracks are, however, difficult to characterize. Our aim here is to assess the effectiveness of three‐dimensional electrical resistivity surveys in detecting soil crack networks.
Samouëlian, Anatja   +5 more
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

PLASTICITY AREA AT THE THREE DIMENSIONAL CURVED ELASTICITY-PLASTICITY CRACK TIP UNDER QUASI-STATIC LOAD

open access: yesJixie qiangdu, 2018
In this article,three dimensional elastic-plastic curved crack tip plasticity area under quasi-static loads has been mainly studied,and three dimensional curved crack tip plasticity area has been calculated as a practical application of a second order ...
YANG DaPeng   +3 more
doaj  

Fatigue assessment and crack propagation of floorbeam cutout in orthotropic bridge decks

open access: yesMaterials & Design, 2023
Based on the fatigue cracking of floorbeam cutout in a bridge, the field testing under random traffic flows was firstly conducted to investigate the fatigue crack initiation, and then a multi-scale numerical model, based on extended finite element method
Ze Xiang, Zhiwen Zhu, Xinbin Lei
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy